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Virma Gene Detail
Summary
  • Symbol
    Virma
  • Name
    vir like m6A methyltransferase associated
  • Synonyms
    1110037F02Rik, 4930422M05Rik, mKIAA1429
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913435
    NCBI Gene: 66185
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:11485958-11550684 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 5.11 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1753 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913435
 protein coding gene Chr4:11485958-11551143 (+)
129S1/SvImJ ENSMUSG00200001192
 protein coding gene Chr4:8123927-8188687 (+)
A/J ENSMUSG00195002731
 protein coding gene Chr4:8565530-8630264 (+)
AKR/J ENSMUSG00220001018
 protein coding gene Chr4:8314419-8379293 (+)
BALB/cJ ENSMUSG00180004478
 protein coding gene Chr4:8085784-8150555 (+)
C3H/HeJ ENSMUSG00175016523
 protein coding gene Chr4:8605409-8670281 (+)
C57BL/6NJ ENSMUSG00215004496
 protein coding gene Chr4:8230143-8294905 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025809
 protein coding gene Chr4:7533794-7599746 (+)
CAST/EiJ ENSTCUG00005024598
 protein coding gene Chr4:8283770-8349028 (+)
CBA/J ENSMUSG00210002358
 protein coding gene Chr4:8345139-8410010 (+)
DBA/2J ENSMUSG00185002406
 protein coding gene Chr4:8454349-8519220 (+)
FVB/NJ ENSMUSG00205003173
 protein coding gene Chr4:8115203-8179894 (+)
JF1/MsJ ENSUMUG00000001372
 protein coding gene Chr4:8559955-8624338 (+)
LP/J ENSMUSG00230000975
 protein coding gene Chr4:11635409-11700163 (+)
NOD/ShiLtJ ENSMUSG00190012888
 protein coding gene Chr4:8192982-8257710 (+)
NZO/HlLtJ ENSMUSG00225008258
 protein coding gene Chr4:15646362-15711048 (+)
PWK/PhJ ENSLUMG00010005288
 protein coding gene Chr4:8034577-8098885 (+)
SPRET/EiJ ENSMSPG00010002590
 protein coding gene Chr4:8375347-8438238 (+)
WSB/EiJ ENSIUOG00005013712
 protein coding gene Chr4:8130691-8195387 (+)



Homology
more
  • Human Ortholog
    VIRMA, vir like m6A methyltransferase associated
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VIRMA, vir like m6A methyltransferase associated
  • Synonyms
    fSAP121, KIAA1429, MSTP054
  • Links
    NCBI Gene ID: 25962
    UniProt: Q69YN4

  • Chr Location
    8q22.1; chr8:94487689-94553529 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal trophoblast layer formation, partial embryonic during organogenesis and complete lethality by E14.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    684
  • Tissues
    8
  • cDNA Data
    164
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040720 Ensembl Gene Model | MGI Sequence Detail 64727 C57BL/6J ±  kb
transcript ENSMUST00000108307 Ensembl | MGI Sequence Detail 6571 Not Applicable  
polypeptide ENSMUSP00000103943 Ensembl | MGI Sequence Detail 1861 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 165
    cDNA 164
    Primer pair 1
    Antibodies 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:2442597, MGI:5898323
References
more
  • Summaries
    All 50
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 18
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:368729 Wu M, et al., VIRMA-mediated m(6)A modification regulates forebrain formation through modulating ribosome biogenesis. Sci Adv. 2025 Jun 27;11(26):eadq9643
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory