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Dtd1 Gene Detail
Summary
  • Symbol
    Dtd1
  • Name
    D-tyrosyl-tRNA deacylase 1
  • Synonyms
    0610006H08Rik, Hars2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913294
    NCBI Gene: 66044
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:144441873-144610667 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 71.02 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3713 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913294
 protein coding gene Chr2:144441817-144610678 (+)
129S1/SvImJ ENSMUSG00200007227
 protein coding gene Chr2:141508862-141669578 (+)
A/J ENSMUSG00195019171
 protein coding gene Chr2:141685584-141854319 (+)
AKR/J ENSMUSG00220037302
 protein coding gene Chr2:141227123-141393879 (+)
BALB/cJ ENSMUSG00180026667
 protein coding gene Chr2:141341982-141510721 (+)
C3H/HeJ ENSMUSG00175030314
 protein coding gene Chr2:141889096-142057825 (+)
C57BL/6NJ ENSMUSG00215020294
 protein coding gene Chr2:141397940-141566680 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024389
 protein coding gene Chr2:136861409-137020868 (+)
CAST/EiJ ENSTCUG00005010842
 protein coding gene Chr2:140546346-140712374 (+)
CBA/J ENSMUSG00210038461
 protein coding gene Chr2:141808333-141977060 (+)
DBA/2J ENSMUSG00185040422
 protein coding gene Chr2:141387184-141547915 (+)
FVB/NJ ENSMUSG00205025108
 protein coding gene Chr2:140571082-140740585 (+)
JF1/MsJ ENSUMUG00000028059
 protein coding gene Chr2:141188168-141365243 (+)
LP/J ENSMUSG00230007647
 protein coding gene Chr2:143091273-143252111 (+)
NOD/ShiLtJ ENSMUSG00190028441
 protein coding gene Chr2:141480581-141645314 (+)
NZO/HlLtJ ENSMUSG00225001017
 protein coding gene Chr2:151079401-151240232 (+)
PWK/PhJ ENSLUMG00010039602
 protein coding gene Chr2:141230434-141391320 (+)
SPRET/EiJ ENSMSPG00010023376
 protein coding gene Chr2:143715189-143857014 (+)
WSB/EiJ ENSIUOG00005022338
 protein coding gene Chr2:141253260-141422659 (+)



Homology
more
  • Human Ortholog
    DTD1, D-aminoacyl-tRNA deacylase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DTD1, D-aminoacyl-tRNA deacylase 1
  • Synonyms
    C20orf88, DTD, DUE-B, DUEB, HARS2, pqn-68
  • Links
    NCBI Gene ID: 92675
    UniProt: Q8TEA8

  • Chr Location
    20p11.23; chr20:18587920-18766644 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    694
  • Tissues
    97
  • cDNA Data
    49
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66044 NCBI Gene Model | MGI Sequence Detail 168795 C57BL/6J ±  kb
    transcript NM_025314 RefSeq | MGI Sequence Detail 1283 C57BL/6  
    polypeptide Q9DD18 UniProt | EBI | MGI Sequence Detail 209 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 49
      cDNA 49

      Microarray probesets 3
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 11
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory