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Fetub Gene Detail
Summary
  • Symbol
    Fetub
  • Name
    fetuin beta
  • Synonyms
    2310011O17Rik, D17980
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890221
    NCBI Gene: 59083
  • Alliance
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:22737132-22758518 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 13.76 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890221
protein coding gene Chr16:22737084-22758528 (+)
129S1/SvImJ ENSMUSG00200043917
protein coding gene Chr16:19736986-19762303 (+)
A/J ENSMUSG00195029904
protein coding gene Chr16:19295328-19316776 (+)
AKR/J ENSMUSG00220041188
protein coding gene Chr16:19614735-19636183 (+)
BALB/cJ ENSMUSG00180035735
protein coding gene Chr16:19535922-19557371 (+)
C3H/HeJ ENSMUSG00175045667
protein coding gene Chr16:19680854-19702303 (+)
C57BL/6NJ ENSMUSG00215039360
protein coding gene Chr16:19408058-19429511 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020609
protein coding gene Chr16:20151780-20166720 (+)
CAST/EiJ ENSTCUG00005043690
protein coding gene Chr16:20022233-20037320 (+)
CBA/J ENSMUSG00210038906
protein coding gene Chr16:19702570-19723986 (+)
DBA/2J ENSMUSG00185028628
protein coding gene Chr16:19641321-19662769 (+)
FVB/NJ ENSMUSG00205023517
protein coding gene Chr16:19637245-19663426 (+)
JF1/MsJ ENSUMUG00000044138
protein coding gene Chr16:19870417-19885612 (+)
LP/J ENSMUSG00230032996
protein coding gene Chr16:22220395-22241842 (+)
NOD/ShiLtJ ENSMUSG00190028857
protein coding gene Chr16:19782768-19804213 (+)
NZO/HlLtJ ENSMUSG00225036174
protein coding gene Chr16:25471490-25492934 (+)
PWK/PhJ ENSLUMG00010042914
protein coding gene Chr16:19693685-19708739 (+)
SPRET/EiJ ENSMSPG00010036711
protein coding gene Chr16:19570706-19585572 (+)
WSB/EiJ ENSIUOG00005038661
protein coding gene Chr16:19886434-19901382 (+)



Homology
more
  • Human Ortholog
    FETUB, fetuin B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FETUB, fetuin B
  • Synonyms
    16G2, Gugu, IRL685
  • Links
    NCBI Gene ID: 26998
    UniProt: Q9UGM5

  • Chr Location
    3q27.3; chr3:186634558-186653778 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit female infertility due to premature hardening of the zona pellucida.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic 59083 NCBI Gene Model | MGI Sequence Detail 21387 C57BL/6J ±  kb
    transcript NM_021564 RefSeq | MGI Sequence Detail 1600 ZRU/MplStud  
    polypeptide Q9QXC1 UniProt | EBI | MGI Sequence Detail 388 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 84
      cDNA 83
      Primer pair 1
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1915165, MGI:2146393
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:64478 Olivier E, et al., Fetuin-B, a second member of the fetuin family in mammals. Biochem J. 2000 Sep 1;350 Pt 2:589-97
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory