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Pbsn Gene Detail
Summary
  • Symbol
    Pbsn
  • Name
    probasin
  • Synonyms
    PB
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860484
    NCBI Gene: 54192
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:76881504-76897132 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.32 cM, cytoband A7.1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    285 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860484
 protein coding gene ChrX:76881504-76897229 (-)
129S1/SvImJ ENSMUSG00200040988
 protein coding gene ChrX:58925222-58940945 (-)
A/J ENSMUSG00195040952
 protein coding gene ChrX:62620106-62635815 (-)
AKR/J ENSMUSG00220042459
 protein coding gene ChrX:57728723-57744431 (-)
BALB/cJ ENSMUSG00180049675
 protein coding gene ChrX:59193901-59209610 (-)
C3H/HeJ ENSMUSG00175033027
 protein coding gene ChrX:62772100-62787808 (-)
C57BL/6NJ ENSMUSG00215036804
 protein coding gene ChrX:59290674-59306394 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033204
 protein coding gene ChrX:73238269-73250627 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210043389
 protein coding gene ChrX:59459564-59475276 (-)
DBA/2J ENSMUSG00185037380
 protein coding gene ChrX:71873975-71889685 (-)
FVB/NJ ENSMUSG00205032569
 protein coding gene ChrX:58778260-58793982 (-)
JF1/MsJ ENSUMUG00000020668
 protein coding gene ChrX:92661972-92678781 (-)
LP/J ENSMUSG00230029132
 protein coding gene ChrX:78479275-78494999 (-)
NOD/ShiLtJ ENSMUSG00190032676
 protein coding gene ChrX:58745366-58761086 (-)
NZO/HlLtJ ENSMUSG00225046993
 protein coding gene ChrX:83657073-83672781 (-)
PWK/PhJ ENSLUMG00010043638
 protein coding gene ChrX:58336829-58353591 (-)
SPRET/EiJ ENSMSPG00010022097
 protein coding gene ChrX:61819780-61832274 (-)
WSB/EiJ ENSIUOG00005049237
 protein coding gene ChrX:59463213-59478976 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    2
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 54192 NCBI Gene Model | MGI Sequence Detail 15629 C57BL/6J ±  kb
    transcript NM_017471 RefSeq | MGI Sequence Detail 808 C57BL/6  
    polypeptide O08976 UniProt | EBI | MGI Sequence Detail 174 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 2
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:62973 Johnson MA, et al., Isolation and characterization of mouse probasin: An androgen-regulated protein specifically expressed in the differentiated prostate. Prostate. 2000 Jun 1;43(4):255-62
    • Latest
      J:372669 Lin G, et al., IL-17RA/CTSK axis mediates H. pylori-induced castration-resistant prostate cancer growth. Oncogene. 2024 Nov;43(49):3598-3616
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory