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Cxcl11 Pseudogene Detail
Summary
  • Symbol
    Cxcl11
  • Name
    chemokine (C-X-C motif) ligand 11
  • Synonyms
    betaR1, b-R1, H174, IP9, I-TAC, ITAC, Scyb11, SCYB9B
Location &
Maps
more
  • Sequence Map
    Chr5:92507403-92511155 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 46.61 cM, cytoband E3
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860203
 polymorphic pseudogene Chr5:92507403-92513344 (-)
129S1/SvImJ ENSMUSG00200008002
 protein coding gene Chr5:88259841-88265886 (-)
A/J ENSMUSG00195025446
 protein coding gene Chr5:87419081-87425024 (-)
AKR/J ENSMUSG00220011651
 protein coding gene Chr5:87562606-87568592 (-)
BALB/cJ ENSMUSG00180025126
 protein coding gene Chr5:87257018-87263010 (-)
C3H/HeJ ENSMUSG00175038853
 protein coding gene Chr5:89357786-89363780 (-)
C57BL/6NJ ENSMUSG00215018317
 protein coding gene Chr5:88107697-88113638 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008955
 polymorphic pseudogene Chr5:85477860-85483795 (-)
CAST/EiJ ENSTCUG00005035597
 protein coding gene Chr5:86978734-86984607 (-)
CBA/J ENSMUSG00210004428
 protein coding gene Chr5:88136519-88142509 (-)
DBA/2J ENSMUSG00185036970
 protein coding gene Chr5:90073257-90079241 (-)
FVB/NJ ENSMUSG00205023301
 protein coding gene Chr5:86961962-86967952 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230025153
 protein coding gene Chr5:94771048-94777091 (-)
NOD/ShiLtJ ENSMUSG00190034215
 protein coding gene Chr5:87039026-87044973 (-)
NZO/HlLtJ ENSMUSG00225009053
 protein coding gene Chr5:99910298-99916243 (-)
PWK/PhJ ENSLUMG00010027965
 protein coding gene Chr5:87003350-87009379 (-)
SPRET/EiJ ENSMSPG00010031687
 protein coding gene Chr5:89378638-89382357 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CXCL11, C-X-C motif chemokine ligand 11
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CXCL11, C-X-C motif chemokine ligand 11
  • Synonyms
    b-R1, H174, IP-9, IP9, I-TAC, SCYB11, SCYB9B
  • Links
    NCBI Gene ID: 6373
    UniProt: O14625

  • Chr Location
    4q21.1; chr4:76033682-76041415 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    5
  • Radiation induced
    1
  • Spontaneous
    2
  • Genomic Mutations
    3 involving Cxcl11
  • Find Mice (IMSR)
    8 strains or lines available
Mice with null or restored expression show similar adaptive immune responses to viral infection.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    26
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • Tissues
    20
  • cDNA Data
    13
  • Literature Summary
    6
Sequences &
Gene Models
less
  • All Sequences
    35
  • RefSeq
    3
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 56066 NCBI Gene Model | MGI Sequence Detail 3753 C57BL/6J ±  kb
transcript NR_038116 RefSeq | MGI Sequence Detail 1605 C57BL/6  
polypeptide Q9JHH5 UniProt | EBI | MGI Sequence Detail 100 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 13
    Primer pair 3
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 74
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:372136 Feng Z, et al., Chemokine (C-X-C motif) ligand 11 is a crucial antiviral modulator that affects viral replication, the IFN-gamma response, and T-cell functions during respiratory syncytial virus infection. J Immunol. 2025 Aug 1;214(8):1982-1999
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory