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Whr1 Gene Detail
Summary
  • Symbol
    Whr1
  • Name
    winged helix repair factor 1
  • Synonyms
    G11, RP1, Stk19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860085
    NCBI Gene: 54402
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35042969-35055879 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860085
protein coding gene Chr17:35042969-35055921 (-)
129S1/SvImJ ENSMUSG00200050100
protein coding gene Chr17:30746146-30759102 (-)
A/J ENSMUSG00195039592
protein coding gene Chr17:31646342-31659342 (-)
AKR/J ENSMUSG00220049772
protein coding gene Chr17:30674967-30687923 (-)
BALB/cJ ENSMUSG00180038657
protein coding gene Chr17:31016210-31029211 (-)
C3H/HeJ ENSMUSG00175033019
protein coding gene Chr17:30561075-30574032 (-)
C57BL/6NJ ENSMUSG00215050335
protein coding gene Chr17:30586333-30599287 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021475
protein coding gene Chr17:31545549-31571755 (-)
CAST/EiJ ENSTCUG00005047969
protein coding gene Chr17:31604544-31617509 (-)
CBA/J ENSMUSG00210052005
protein coding gene Chr17:30383183-30396140 (-)
DBA/2J ENSMUSG00185050466
protein coding gene Chr17:33035476-33048476 (-)
FVB/NJ ENSMUSG00205051597
protein coding gene Chr17:30904902-30917901 (-)
JF1/MsJ ENSUMUG00000056875
protein coding gene Chr17:32287920-32300889 (-)
LP/J ENSMUSG00230054610
protein coding gene Chr17:34144413-34157365 (-)
NOD/ShiLtJ ENSMUSG00190051241
protein coding gene Chr17:30505872-30518942 (-)
NZO/HlLtJ ENSMUSG00225053738
protein coding gene Chr17:36157394-36170381 (-)
PWK/PhJ ENSLUMG00010051422
protein coding gene Chr17:30115133-30135844 (-)
SPRET/EiJ ENSMSPG00010047677
protein coding gene Chr17:31308101-31321399 (-)
WSB/EiJ ENSIUOG00005051060
protein coding gene Chr17:31233719-31246694 (-)



Homology
more
  • Human Ortholog
    WHR1, winged helix repair factor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WHR1, winged helix repair factor 1
  • Synonyms
    D6S60, D6S60E, G11, HLA-RP1, RP1, STK19, TWH19
  • Links
    NCBI Gene ID: 8859
    UniProt: P49842

  • Chr Location
    6p21.33; chr6:31971091-31982821 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 54402 NCBI Gene Model | MGI Sequence Detail 12911 C57BL/6J ±  kb
transcript NM_019442 RefSeq | MGI Sequence Detail 1078 C57BL/6  
polypeptide Q9JHN8 UniProt | EBI | MGI Sequence Detail 254 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    Genomic 1
    cDNA 34

    Microarray probesets 2
Other
Accession IDs
less
MGI:8329955
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:63110 Allcock RJ, et al., The mouse as a model for the effects of MHC genes on human disease. Immunol Today. 2000 Jul;21(7):328-32
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory