About   Help   FAQ
Actr1a Gene Detail
Summary
  • Symbol
    Actr1a
  • Name
    ARP1 actin-related protein 1A, centractin alpha
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858964
    NCBI Gene: 54130
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:46365252-46384180 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 38.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    601 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858964
 protein coding gene Chr19:46365250-46384187 (-)
129S1/SvImJ ENSMUSG00200020651
 protein coding gene Chr19:43065554-43085098 (-)
A/J ENSMUSG00195013895
 protein coding gene Chr19:43199923-43218863 (-)
AKR/J ENSMUSG00220018484
 protein coding gene Chr19:43002092-43021629 (-)
BALB/cJ ENSMUSG00180019029
 protein coding gene Chr19:43452171-43471110 (-)
C3H/HeJ ENSMUSG00175006379
 protein coding gene Chr19:42994587-43014121 (-)
C57BL/6NJ ENSMUSG00215004178
 protein coding gene Chr19:43063187-43082124 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023036
 protein coding gene Chr19:43033046-43051793 (-)
CAST/EiJ ENSTCUG00005015931
 protein coding gene Chr19:42651513-42670967 (-)
CBA/J ENSMUSG00210018237
 protein coding gene Chr19:43074106-43093636 (-)
DBA/2J ENSMUSG00185007378
 protein coding gene Chr19:43575614-43594550 (-)
FVB/NJ ENSMUSG00205017149
 protein coding gene Chr19:42489279-42508829 (-)
JF1/MsJ ENSUMUG00000021402
 protein coding gene Chr19:43733033-43751962 (-)
LP/J ENSMUSG00230023939
 protein coding gene Chr19:44335208-44354751 (-)
NOD/ShiLtJ ENSMUSG00190005286
 protein coding gene Chr19:42939447-42958989 (-)
NZO/HlLtJ ENSMUSG00225043319
 protein coding gene Chr19:47931179-47950717 (-)
PWK/PhJ ENSLUMG00010000906
 protein coding gene Chr19:42899044-42917945 (-)
SPRET/EiJ ENSMSPG00010006886
 protein coding gene Chr19:42639302-42658250 (-)
WSB/EiJ ENSIUOG00005006331
 protein coding gene Chr19:42437997-42457516 (-)



Homology
more
  • Human Ortholog
    ACTR1A, actin related protein 1A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACTR1A, actin related protein 1A
  • Synonyms
    ARP1, Arp1A, CTRN1
  • Links
    NCBI Gene ID: 10121
    UniProt: P61163

  • Chr Location
    10q24.32; chr10:102461881-102502744 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    676
  • Tissues
    13
  • cDNA Data
    255
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54130 NCBI Gene Model | MGI Sequence Detail 18929 C57BL/6J ±  kb
transcript NM_016860 RefSeq | MGI Sequence Detail 2766 C57BL/6  
polypeptide P61164 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 257
    cDNA 257
    Antibodies 1

    Microarray probesets 6
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:57581 Kusano K, et al., Primary structure of mouse actin-related protein 1 (Arp1) and its tissue expression. Zoolog Sci. 1997 Feb;14(1):77-82
  • Latest
    J:282974 Lee M, et al., Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain. J Cell Biol. 2020 Feb 3;219(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory