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Fbh1 Gene Detail
Summary
  • Symbol
    Fbh1
  • Name
    F-box DNA helicase 1
  • Synonyms
    Fbx18, Fbxo18
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354699
    NCBI Gene: 50755
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:11747384-11782393 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 9.01 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    928 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354699
 protein coding gene Chr2:11747384-11782396 (-)
129S1/SvImJ ENSMUSG00200029459
 protein coding gene Chr2:8644201-8680821 (-)
A/J ENSMUSG00195016787
 protein coding gene Chr2:8765056-8801676 (-)
AKR/J ENSMUSG00220005763
 protein coding gene Chr2:8734388-8771008 (-)
BALB/cJ ENSMUSG00180030223
 protein coding gene Chr2:8814946-8851567 (-)
C3H/HeJ ENSMUSG00175016418
 protein coding gene Chr2:8749247-8785867 (-)
C57BL/6NJ ENSMUSG00215008715
 protein coding gene Chr2:8829127-8865747 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023178
 protein coding gene Chr2:8211569-8245757 (-)
CAST/EiJ ENSTCUG00005004668
 protein coding gene Chr2:8633492-8670134 (-)
CBA/J ENSMUSG00210026458
 protein coding gene Chr2:8795277-8831898 (-)
DBA/2J ENSMUSG00185012504
 protein coding gene Chr2:8710213-8746833 (-)
FVB/NJ ENSMUSG00205022011
 protein coding gene Chr2:8703741-8740362 (-)
JF1/MsJ ENSUMUG00000003141
 protein coding gene Chr2:8688937-8725477 (-)
LP/J ENSMUSG00230019065
 protein coding gene Chr2:10656497-10693117 (-)
NOD/ShiLtJ ENSMUSG00190005841
 protein coding gene Chr2:8731952-8768563 (-)
NZO/HlLtJ ENSMUSG00225001191
 protein coding gene Chr2:18402361-18438981 (-)
PWK/PhJ ENSLUMG00010027743
 protein coding gene Chr2:8803284-8839877 (-)
SPRET/EiJ ENSMSPG00010026963
 protein coding gene Chr2:8875549-8912861 (-)
WSB/EiJ ENSIUOG00005022706
 protein coding gene Chr2:8784360-8820729 (-)



Homology
more
  • Human Ortholog
    FBH1, F-box DNA helicase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBH1, F-box DNA helicase 1
  • Synonyms
    Fbx18, FBXO18, hFBH1
  • Links
    NCBI Gene ID: 84893
    UniProt: Q8NFZ0

  • Chr Location
    10p15.1; chr10:5889572-5937594 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    63
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    130
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058594 Ensembl Gene Model | MGI Sequence Detail 35010 C57BL/6J ±  kb
transcript ENSMUST00000071564 Ensembl | MGI Sequence Detail 3567 Not Applicable  
polypeptide ENSMUSP00000071495 Ensembl | MGI Sequence Detail 1042 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 130
    cDNA 130

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139155, MGI:6188850
References
more
  • Summaries
    All 43
    Developmental Gene Expression 1
    Gene Ontology 13
    Phenotypes 6
  • Earliest
    J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory