About   Help   FAQ
Aoah Gene Detail
Summary
  • Symbol
    Aoah
  • Name
    acyloxyacyl hydrolase
  • Synonyms
    4930433E13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1350928
    NCBI Gene: 27052
  • Alliance
  • Transcription Start Sites
    133 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:20978283-21220787 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 7.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7007 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350928
protein coding gene Chr13:20978273-21220787 (+)
129S1/SvImJ no annotation
A/J ENSMUSG00195033747
protein coding gene Chr13:17321025-17544478 (+)
AKR/J ENSMUSG00220030136
protein coding gene Chr13:17235116-17459818 (+)
BALB/cJ ENSMUSG00180032883
protein coding gene Chr13:17681565-17905753 (+)
C3H/HeJ ENSMUSG00175029086
protein coding gene Chr13:17786708-18010895 (+)
C57BL/6NJ ENSMUSG00215025026
protein coding gene Chr13:17733861-17964026 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018259
protein coding gene Chr13:16057956-16260991 (+)
CAST/EiJ ENSTCUG00005013293
protein coding gene Chr13:17809535-18019245 (+)
CBA/J ENSMUSG00210027633
protein coding gene Chr13:17641269-17872492 (+)
DBA/2J ENSMUSG00185012590
protein coding gene Chr13:18342656-18566848 (+)
FVB/NJ ENSMUSG00205043066
protein coding gene Chr13:17503560-17719559 (+)
JF1/MsJ ENSUMUG00000018333
protein coding gene Chr13:18064966-18286128 (+)
LP/J ENSMUSG00230030327
protein coding gene Chr13:27736703-27960898 (+)
NOD/ShiLtJ ENSMUSG00190020605
protein coding gene Chr13:17596026-17825683 (+)
NZO/HlLtJ ENSMUSG00225043492
protein coding gene Chr13:21498024-21728220 (+)
PWK/PhJ ENSLUMG00010025614
protein coding gene Chr13:17050112-17275092 (+)
SPRET/EiJ ENSMSPG00010016566
protein coding gene Chr13:16749050-16974524 (+)
WSB/EiJ ENSIUOG00005034550
protein coding gene Chr13:16972200-17202095 (+)



Homology
more
  • Human Ortholog
    AOAH, acyloxyacyl hydrolase
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AOAH, acyloxyacyl hydrolase
  • Links
    NCBI Gene ID: 313
    UniProt: P28039

  • Chr Location
    7p14.2; chr7:36509308-36724549 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    36 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice have a reduced ability to deacylate bacterial lipopolysaccharides.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021322 Ensembl Gene Model | MGI Sequence Detail 242505 C57BL/6J ±  kb
transcript ENSMUST00000021757 Ensembl | MGI Sequence Detail 2921 Not Applicable  
polypeptide ENSMUSP00000021757 Ensembl | MGI Sequence Detail 574 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921929
References
more
  • Summaries
    All 71
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 36
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:379842 Gan L, et al., Acyloxyacyl Hydrolase Prevents Colitis and Colitis-Associated Colorectal Cancer by Inactivating Stimulatory LPS in the Intestine. FASEB J. 2025 Apr 30;39(8):e70566

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/08/2026
MGI 6.24
The Jackson Laboratory