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Serinc3 Gene Detail
Summary
  • Symbol
    Serinc3
  • Name
    serine incorporator 3
  • Synonyms
    AIGP1, DIFF33, Tde1, TMS-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349457
    NCBI Gene: 26943
  • Alliance
    genome feature page
  • Transcription Start Sites
    26 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:163466577-163487767 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 84.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    574 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349457
 protein coding gene Chr2:163465192-163487767 (-)
129S1/SvImJ ENSMUSG00200016697
 protein coding gene Chr2:160360565-160382330 (-)
A/J ENSMUSG00195015822
 protein coding gene Chr2:160700620-160722488 (-)
AKR/J ENSMUSG00220013737
 protein coding gene Chr2:160027954-160049805 (-)
BALB/cJ ENSMUSG00180046222
 protein coding gene Chr2:160154352-160176215 (-)
C3H/HeJ ENSMUSG00175050752
 protein coding gene Chr2:160904112-160925974 (-)
C57BL/6NJ ENSMUSG00215036490
 protein coding gene Chr2:160335050-160356910 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024620
 protein coding gene Chr2:155468923-155490274 (-)
CAST/EiJ ENSTCUG00005044372
 protein coding gene Chr2:159268282-159290915 (-)
CBA/J ENSMUSG00210015471
 protein coding gene Chr2:160835140-160857002 (-)
DBA/2J ENSMUSG00185046475
 protein coding gene Chr2:160571288-160593139 (-)
FVB/NJ ENSMUSG00205019753
 protein coding gene Chr2:159594129-159615986 (-)
JF1/MsJ ENSUMUG00000007592
 protein coding gene Chr2:160212434-160234665 (-)
LP/J ENSMUSG00230042121
 protein coding gene Chr2:162109758-162152125 (-)
NOD/ShiLtJ ENSMUSG00190037635
 protein coding gene Chr2:160211233-160233084 (-)
NZO/HlLtJ ENSMUSG00225051495
 protein coding gene Chr2:170133656-170155507 (-)
PWK/PhJ ENSLUMG00010040905
 protein coding gene Chr2:160118900-160140703 (-)
SPRET/EiJ ENSMSPG00010027226
 protein coding gene Chr2:162888353-162910105 (-)
WSB/EiJ ENSIUOG00005040188
 protein coding gene Chr2:159959664-159981519 (-)



Homology
more
  • Human Ortholog
    SERINC3, serine incorporator 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERINC3, serine incorporator 3
  • Synonyms
    AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1
  • Links
    NCBI Gene ID: 10955
    UniProt: Q13530

  • Chr Location
    20q13.12; chr20:44496221-44522094 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    698
  • Tissues
    12
  • cDNA Data
    28
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 26943 NCBI Gene Model | MGI Sequence Detail 21191 C57BL/6J ±  kb
    transcript NM_001412448 RefSeq | MGI Sequence Detail 2533 C57BL/6  
    polypeptide Q9QZI9 UniProt | EBI | MGI Sequence Detail 472 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 28
      cDNA 28

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2138812, MGI:2138813
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 13
    • Earliest
      J:20131 Kerr SM, et al., Analysis of cDNA sequences from mouse testis. Mamm Genome. 1994 Sep;5(9):557-65
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory