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Vat1 Gene Detail
Summary
  • Symbol
    Vat1
  • Name
    vesicle amine transport 1
  • Synonyms
    VAT-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1349450
    NCBI Gene: 26949
  • Alliance
    genome feature page
  • Transcription Start Sites
    21 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101349574-101357025 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 65.10 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    215 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1349450
 protein coding gene Chr11:101349571-101357056 (-)
129S1/SvImJ ENSMUSG00200048480
 protein coding gene Chr11:98619965-98627450 (-)
A/J ENSMUSG00195051363
 protein coding gene Chr11:98313552-98321060 (-)
AKR/J ENSMUSG00220046929
 protein coding gene Chr11:98549935-98557420 (-)
BALB/cJ ENSMUSG00180047565
 protein coding gene Chr11:98682164-98689649 (-)
C3H/HeJ ENSMUSG00175042598
 protein coding gene Chr11:98593511-98600994 (-)
C57BL/6NJ ENSMUSG00215052019
 protein coding gene Chr11:98169587-98177072 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017221
 protein coding gene Chr11:97338356-97346005 (-)
CAST/EiJ ENSTCUG00005048439
 protein coding gene Chr11:98089886-98097431 (-)
CBA/J ENSMUSG00210053117
 protein coding gene Chr11:98315404-98322889 (-)
DBA/2J ENSMUSG00185044437
 protein coding gene Chr11:98643364-98650847 (-)
FVB/NJ ENSMUSG00205044505
 protein coding gene Chr11:98500281-98507766 (-)
JF1/MsJ ENSUMUG00000054923
 protein coding gene Chr11:98907512-98915018 (-)
LP/J ENSMUSG00230048228
 protein coding gene Chr11:99695998-99703481 (-)
NOD/ShiLtJ ENSMUSG00190036859
 protein coding gene Chr11:98681925-98689408 (-)
NZO/HlLtJ ENSMUSG00225052073
 protein coding gene Chr11:101731980-101739461 (-)
PWK/PhJ ENSLUMG00010039674
 protein coding gene Chr11:98450269-98457599 (-)
SPRET/EiJ ENSMSPG00010047061
 protein coding gene Chr11:98934290-98940642 (-)
WSB/EiJ ENSIUOG00005044469
 protein coding gene Chr11:98443772-98451266 (-)



Homology
more
  • Human Ortholog
    VAT1, vesicle amine transport 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VAT1, vesicle amine transport 1
  • Synonyms
    MIB, VAT-1, VATI
  • Links
    NCBI Gene ID: 10493
    UniProt: Q99536

  • Chr Location
    17q21.31; chr17:43010692-43025123 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    5
  • cDNA Data
    144
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 26949 NCBI Gene Model | MGI Sequence Detail 7452 C57BL/6J ±  kb
transcript NM_012037 RefSeq | MGI Sequence Detail 2732 C57BL/6  
polypeptide Q62465 UniProt | EBI | MGI Sequence Detail 406 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 146
    Genomic 2
    cDNA 144

    Microarray probesets 3
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 13
  • Earliest
    J:57580 Hayess K, et al., Mammalian protein homologous to VAT-1 of Torpedo californica: isolation from Ehrlich ascites tumor cells, biochemical characterization, and organization of its gene. J Cell Biochem. 1998 Jun 1;69(3):304-15
  • Latest
    J:345261 Jia L, et al., MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse. Mol Neurobiol. 2018 Dec;55(12):9089-9099
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory