Krtap15-1 MGI Mouse Gene Detail - MGI:1347350 - keratin associated protein 15-1

Symbol

Krtap15-1
Name

keratin associated protein 15-1
Synonyms

Krtap15, Pmg-2

Feature Type

protein coding gene
IDs

MGI:1347350
NCBI Gene: 26560
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr16:88625897-88626732 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 51.41 cM
Mapping Data

2 experiments

SNPs within 2kb

115 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1347350	protein coding gene	Chr16:88617103-88626732 (+)
129S1/SvImJ	ENSMUSG00200036890	protein coding gene	Chr16:85485957-85495594 (+)
A/J	ENSMUSG00195026059	protein coding gene	Chr16:85296182-85305809 (+)
AKR/J	ENSMUSG00220015406	protein coding gene	Chr16:85480444-85490074 (+)
BALB/cJ	ENSMUSG00180014014	protein coding gene	Chr16:85369450-85379078 (+)
C3H/HeJ	ENSMUSG00175014892	protein coding gene	Chr16:85707678-85717307 (+)
C57BL/6NJ	ENSMUSG00215024228	protein coding gene	Chr16:85498088-85507717 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020917	protein coding gene	Chr16:83305640-83315356 (+)
CAST/EiJ	ENSTCUG00005017806	protein coding gene	Chr16:85059448-85069149 (+)
CBA/J	ENSMUSG00210032145	protein coding gene	Chr16:85590661-85600288 (+)
DBA/2J	ENSMUSG00185030656	protein coding gene	Chr16:85541960-85551592 (+)
FVB/NJ	ENSMUSG00205012379	protein coding gene	Chr16:85346297-85355923 (+)
JF1/MsJ	ENSUMUG00000028300	protein coding gene	Chr16:85706006-85715652 (+)
LP/J	ENSMUSG00230030587	protein coding gene	Chr16:88045665-88055302 (+)
NOD/ShiLtJ	ENSMUSG00190025177	protein coding gene	Chr16:85523910-85533543 (+)
NZO/HlLtJ	ENSMUSG00225029509	protein coding gene	Chr16:91230576-91240209 (+)
PWK/PhJ	ENSLUMG00010013706	protein coding gene	Chr16:85342942-85352562 (+)
SPRET/EiJ	ENSMSPG00010028426	protein coding gene	Chr16:86486976-86497382 (+)
WSB/EiJ	ENSIUOG00005018829	protein coding gene	Chr16:85479420-85489069 (+)

Human Ortholog

KRTAP15-1, keratin associated protein 15-1

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

KRTAP15-1, keratin associated protein 15-1
Synonyms

KAP15.1
Links

HGNC:18927

NCBI Gene ID: 254950

UniProt: Q3LI76
Chr Location

21q22.11; chr21:30440275-30440869 (+) GRCh38

MGI Vertebrate Homology

Krtap15-1 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: KRTAP15-1
Gene Tree

Krtap15-1

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

3
Targeted

2
Genomic Mutations

3 involving Krtap15-1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

8 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

22

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

34
RefSeq

2
UniProt

2
CCDS

CCDS79477.1

Ensembl

ENSMUSG00000022931 (Evidence)
NCBI Gene

26560

			Length	Strain/Species	Flank
genomic	26560	NCBI Gene Model \| MGI Sequence Detail	836	C57BL/6J	± kb
transcript	NM_013713	RefSeq \| MGI Sequence Detail	836	C57BL/6
polypeptide	Q9QZU5	UniProt \| EBI \| MGI Sequence Detail	150	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000009528 keratin-associated protein 15-1

(term hierarchy)
InterPro Domains

IPR007951 Keratin-associated protein, PMG type

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All nucleic 22

cDNA 22

Microarray probesets 3

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MGI:7540526

Summaries

All 29

Gene Ontology 1

Phenotypes 7
Earliest

J:57027 Kuhn F, et al., Pmg-1 and pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development. Mech Dev. 1999 Aug;86(1-2):193-6
Latest

J:361105 Tateossian H, et al., DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome. Elife. 2025;

TSS for Krtap15-1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr139247	Chr16:88625873-88625888 (+)	-16 bp
Tssr139248	Chr16:88625998-88626023 (+)	114 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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