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Cetn2 Gene Detail
Summary
  • Symbol
    Cetn2
  • Name
    centrin 2
  • Synonyms
    1110034A02Rik, caltractin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347085
    NCBI Gene: 26370
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:71957137-71961967 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 37.29 cM, cytoband B
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    147 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347085
 protein coding gene ChrX:71957137-71962017 (-)
129S1/SvImJ ENSMUSG00200040776
 protein coding gene ChrX:54091228-54096108 (-)
A/J ENSMUSG00195032202
 protein coding gene ChrX:57714025-57718902 (-)
AKR/J ENSMUSG00220044254
 protein coding gene ChrX:53016744-53021621 (-)
BALB/cJ ENSMUSG00180047631
 protein coding gene ChrX:54294845-54299722 (-)
C3H/HeJ ENSMUSG00175030512
 protein coding gene ChrX:57865256-57870133 (-)
C57BL/6NJ ENSMUSG00215040438
 protein coding gene ChrX:54358346-54363225 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033143
 protein coding gene ChrX:67934520-67943458 (-)
CAST/EiJ ENSTCUG00005040834
 protein coding gene ChrX:55798396-55803263 (-)
CBA/J ENSMUSG00210043867
 protein coding gene ChrX:54535844-54540721 (-)
DBA/2J ENSMUSG00185032323
 protein coding gene ChrX:66980755-66985632 (-)
FVB/NJ ENSMUSG00205033008
 protein coding gene ChrX:54029304-54034181 (-)
JF1/MsJ ENSUMUG00000018622
 protein coding gene ChrX:87740804-87745673 (-)
LP/J ENSMUSG00230035639
 protein coding gene ChrX:73539491-73544370 (-)
NOD/ShiLtJ ENSMUSG00190036263
 protein coding gene ChrX:53798454-53803331 (-)
NZO/HlLtJ ENSMUSG00225047779
 protein coding gene ChrX:78743828-78748707 (-)
PWK/PhJ ENSLUMG00010045126
 protein coding gene ChrX:53622038-53626905 (-)
SPRET/EiJ ENSMSPG00010030116
 protein coding gene ChrX:56621531-56626406 (-)
WSB/EiJ ENSIUOG00005047069
 protein coding gene ChrX:54650031-54654908 (-)



Homology
more
  • Human Ortholog
    CETN2, centrin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CETN2, centrin 2
  • Synonyms
    CALT, CEN2
  • Links
    NCBI Gene ID: 1069
    UniProt: P41208

  • Chr Location
    Xq28; chrX:152826994-152830782 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 1 allele in 2 genetic backgrounds
    16 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males hemizygous for a null allele show partial prenatal lethality, dysosmia due to impaired ciliary transport of olfactory signaling proteins, olfactory cilia loss, defective basal body positioning, and hydrocephalus caused by disrupted ependymal cilia planar cell polarity and impaired CSF flow.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    58
  • GO References
    22
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    642
  • Tissues
    3
  • cDNA Data
    55
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 26370 NCBI Gene Model | MGI Sequence Detail 4831 C57BL/6J ±  kb
    transcript NM_019405 RefSeq | MGI Sequence Detail 1237 ZRU/MplStud  
    polypeptide Q9R1K9 UniProt | EBI | MGI Sequence Detail 172 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      Genomic 4
      cDNA 56

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-1741, MGI:1913437, MGI:2147878, MGI:88254
    References
    more
    • Summaries
      All 67
      Developmental Gene Expression 6
      Gene Ontology 22
      Phenotypes 7
    • Earliest
      J:15453 Ogawa K, et al., cDNA sequence for mouse caltractin. Biochim Biophys Acta. 1993 Oct 19;1216(1):126-8
    • Latest
      J:336923 Jiang X, et al., Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Nat Commun. 2023 Jun 22;14(1):3729
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory