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Rpp40 Gene Detail
Summary
  • Symbol
    Rpp40
  • Name
    ribonuclease P 40 subunit
  • Synonyms
    D8Bwg1265e, Rnasep1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1346084
    NCBI Gene: 208366
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:36077455-36090342 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 14.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    529 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1346084
 protein coding gene Chr13:36077455-36095548 (-)
129S1/SvImJ ENSMUSG00200010721
 protein coding gene Chr13:33280299-33293188 (-)
A/J ENSMUSG00195032132
 protein coding gene Chr13:32366772-32379671 (-)
AKR/J ENSMUSG00220029694
 protein coding gene Chr13:32161598-32174491 (-)
BALB/cJ ENSMUSG00180007877
 protein coding gene Chr13:32672453-32685351 (-)
C3H/HeJ ENSMUSG00175011770
 protein coding gene Chr13:32619645-32632542 (-)
C57BL/6NJ ENSMUSG00215010110
 protein coding gene Chr13:32802151-32815041 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018429
 protein coding gene Chr13:31284485-31298373 (-)
CAST/EiJ ENSTCUG00005034331
 protein coding gene Chr13:32691440-32704289 (-)
CBA/J ENSMUSG00210011295
 protein coding gene Chr13:32632184-32645079 (-)
DBA/2J ENSMUSG00185029990
 protein coding gene Chr13:33449576-33462490 (-)
FVB/NJ ENSMUSG00205026800
 protein coding gene Chr13:32328799-32341688 (-)
JF1/MsJ ENSUMUG00000021114
 protein coding gene Chr13:33047251-33060130 (-)
LP/J ENSMUSG00230014421
 protein coding gene Chr13:42775974-42788869 (-)
NOD/ShiLtJ ENSMUSG00190011529
 protein coding gene Chr13:32853944-32866835 (-)
NZO/HlLtJ ENSMUSG00225033668
 protein coding gene Chr13:36586983-36599872 (-)
PWK/PhJ ENSLUMG00010026565
 protein coding gene Chr13:31879457-31892360 (-)
SPRET/EiJ ENSMSPG00010010015
 protein coding gene Chr13:31865419-31875346 (-)
WSB/EiJ ENSIUOG00005026716
 protein coding gene Chr13:32007042-32019937 (-)



Homology
more
  • Human Ortholog
    RPP40, ribonuclease P/MRP subunit p40
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPP40, ribonuclease P/MRP subunit p40
  • Synonyms
    bA428J1.3, RNASEP1
  • Links
    NCBI Gene ID: 10799
    UniProt: O75818

  • Chr Location
    6p25.1; chr6:4988426-5004063 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    691
  • Tissues
    94
  • cDNA Data
    17
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021418 Ensembl Gene Model | MGI Sequence Detail 12888 C57BL/6J ±  kb
transcript ENSMUST00000171686 Ensembl | MGI Sequence Detail 4380 Not Applicable  
polypeptide ENSMUSP00000130290 Ensembl | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-34123, MGI:106429
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory