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Psmd13 Gene Detail
Summary
  • Symbol
    Psmd13
  • Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • Synonyms
    26S proteasome subunit p40.5, S11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345192
    NCBI Gene: 23997
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140462307-140478555 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 86.09 cM, cytoband F5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    427 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345192
protein coding gene Chr7:140461881-140478556 (+)
129S1/SvImJ ENSMUSG00200043413
protein coding gene Chr7:127026624-127043303 (+)
A/J ENSMUSG00195039079
protein coding gene Chr7:131509055-131525734 (+)
AKR/J ENSMUSG00220029608
protein coding gene Chr7:124980408-124997087 (+)
BALB/cJ ENSMUSG00180029801
protein coding gene Chr7:128201216-128217895 (+)
C3H/HeJ ENSMUSG00175035336
protein coding gene Chr7:128929526-128946207 (+)
C57BL/6NJ ENSMUSG00215045676
protein coding gene Chr7:128196071-128212751 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030665
protein coding gene Chr7:143076376-143090985 (+)
CAST/EiJ ENSTCUG00005048717
protein coding gene Chr7:131502546-131519240 (+)
CBA/J ENSMUSG00210029890
protein coding gene Chr7:128687471-128704172 (+)
DBA/2J ENSMUSG00185017250
protein coding gene Chr7:132966085-132982764 (+)
FVB/NJ ENSMUSG00205044031
protein coding gene Chr7:128608348-128625028 (+)
JF1/MsJ ENSUMUG00000017640
protein coding gene Chr7:138043915-138059076 (+)
LP/J ENSMUSG00230038933
protein coding gene Chr7:139129586-139146265 (+)
NOD/ShiLtJ ENSMUSG00190019782
protein coding gene Chr7:128794994-128811673 (+)
NZO/HlLtJ ENSMUSG00225048655
protein coding gene Chr7:137338824-137355503 (+)
PWK/PhJ ENSLUMG00010043933
protein coding gene Chr7:127174748-127191470 (+)
SPRET/EiJ ENSMSPG00010036913
protein coding gene Chr7:128615349-128630977 (+)
WSB/EiJ ENSIUOG00005029837
protein coding gene Chr7:129530002-129546708 (+)



Homology
more
  • Human Ortholog
    PSMD13, proteasome 26S subunit, non-ATPase 13
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMD13, proteasome 26S subunit, non-ATPase 13
  • Synonyms
    HSPC027, p40.5, Rpn9, S11
  • Links
    NCBI Gene ID: 5719
    UniProt: Q9UNM6

  • Chr Location
    11p15.5; chr11:236966-252986 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 23997 NCBI Gene Model | MGI Sequence Detail 16249 C57BL/6J ±  kb
transcript NM_011875 RefSeq | MGI Sequence Detail 1563 C57BL/6  
polypeptide Q9WVJ2 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000002179 26S proteasome non-ATPase regulatory subunit 13
  • InterPro Domains
    IPR035298 26S Proteasome non-ATPase regulatory subunit 13
    IPR000717 Proteasome component (PCI) domain
    IPR054179 PSD13, N-terminal
    IPR036390 Winged helix DNA-binding domain superfamily
  • GlyGen
    Q9WVJ2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
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  • All nucleic 178
    cDNA 178

    Microarray probesets 3
References
more
  • Summaries
    All 49
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:54629 Hoffman L, et al., Identification, molecular cloning, and characterization of subunit 11 of the human 26S proteasome. FEBS Lett. 1999 Apr 16;449(1):88-92
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory