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Rbmx Gene Detail
Summary
  • Symbol
    Rbmx
  • Name
    RNA binding motif protein, X chromosome
  • Feature Type
    protein coding gene
  • IDs
    MGI:1343044
    NCBI Gene: 19655
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:56428890-56438396 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 31.64 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    224 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1343044
 protein coding gene ChrX:56428708-56438405 (-)
129S1/SvImJ ENSMUSG00200037152
 protein coding gene ChrX:38762314-38763869 (-)
129S1/SvImJ ENSMUSGG00200054715
 protein coding gene ChrX:38759082-38762406 (-)
A/J ENSMUSGG00195055273
 protein coding gene ChrX:42193640-42196959 (-)
A/J ENSMUSG00195009317
 protein coding gene ChrX:42196867-42198422 (-)
AKR/J ENSMUSGG00220054622
 protein coding gene ChrX:38084839-38088163 (-)
AKR/J ENSMUSG00220038196
 protein coding gene ChrX:38088071-38089626 (-)
BALB/cJ ENSMUSGG00180055283
 protein coding gene ChrX:38825919-38829238 (-)
BALB/cJ ENSMUSG00180032909
 protein coding gene ChrX:38829146-38830701 (-)
C3H/HeJ ENSMUSGG00175055132
 protein coding gene ChrX:42355182-42358501 (-)
C3H/HeJ ENSMUSG00175040906
 protein coding gene ChrX:42358409-42359964 (-)
C57BL/6NJ ENSMUSG00215047387
 protein coding gene ChrX:39021052-39022607 (-)
C57BL/6NJ ENSMUSGG00215055760
 protein coding gene ChrX:39017825-39021144 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033098
 protein coding gene ChrX:52308000-52317687 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054799
 protein coding gene ChrX:39187238-39190562 (-)
CBA/J ENSMUSG00210036221
 protein coding gene ChrX:39190470-39192025 (-)
DBA/2J ENSMUSG00185034022
 protein coding gene ChrX:51509105-51510660 (-)
DBA/2J ENSMUSGG00185057355
 protein coding gene ChrX:51505873-51509197 (-)
FVB/NJ ENSMUSG00205025794
 protein coding gene ChrX:38837883-38839438 (-)
FVB/NJ ENSMUSGG00205054068
 protein coding gene ChrX:38834651-38837975 (-)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055366
 protein coding gene ChrX:58035984-58039308 (-)
LP/J ENSMUSG00230028544
 protein coding gene ChrX:58039216-58040771 (-)
NOD/ShiLtJ ENSMUSG00190033118
 protein coding gene ChrX:38521241-38522796 (-)
NOD/ShiLtJ ENSMUSGG00190054915
 protein coding gene ChrX:38518009-38521333 (-)
NZO/HlLtJ ENSMUSG00225032360
 protein coding gene ChrX:63280391-63281946 (-)
NZO/HlLtJ ENSMUSGG00225055178
 protein coding gene ChrX:63277164-63280483 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010022581
 protein coding gene ChrX:40914984-40922946 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RBMX, RNA binding motif protein X-linked
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBMX, RNA binding motif protein X-linked
  • Synonyms
    hnRNP-G, HNRNPG, HNRPG, MRXS11, MRXSG, MRXSH, RBMXRT, RNMX
  • Links
    NCBI Gene ID: 27316
    UniProt: P38159

  • Chr Location
    Xq26.3; chrX:136848004-136880764 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human RBMX associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 3 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    675
  • Tissues
    58
  • cDNA Data
    150
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031134 Ensembl Gene Model | MGI Sequence Detail 9507 C57BL/6J ±  kb
    transcript ENSMUST00000114726 Ensembl | MGI Sequence Detail 2108 Not Applicable  
    polypeptide ENSMUSP00000110374 Ensembl | MGI Sequence Detail 391 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000013813 RNA-binding motif protein, X chromosome
      (term hierarchy)
    • InterPro Domains
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR012604 RBM1CTR
      IPR035979 RNA-binding domain superfamily
      IPR050441 RNA-binding motif
      IPR000504 RNA recognition motif domain
      IPR003954 RNA recognition motif domain, eukaryotic-type
    • GlyGen
      Q9WV02 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 151
      cDNA 150
      Primer pair 1

      Microarray probesets 10
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 15
    • Earliest
      J:55846 Mazeyrat S, et al., RBMY evolved on the Y chromosome from a ubiquitously transcribed X-Y identical gene [letter]. Nat Genet. 1999 Jul;22(3):224-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory