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Cdh22 Gene Detail
Summary
  • Symbol
    Cdh22
  • Name
    cadherin 22
  • Synonyms
    PB-cadherin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341843
    NCBI Gene: 104010
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164953427-165076773 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3476 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341843
 protein coding gene Chr2:164953421-165076892 (-)
129S1/SvImJ ENSMUSG00200016448
 protein coding gene Chr2:161842308-161965949 (-)
A/J ENSMUSG00195024616
 protein coding gene Chr2:162174873-162298170 (-)
AKR/J ENSMUSG00220011752
 protein coding gene Chr2:161504248-161627513 (-)
BALB/cJ ENSMUSG00180036255
 protein coding gene Chr2:161628582-161751880 (-)
C3H/HeJ ENSMUSG00175038828
 protein coding gene Chr2:162379042-162502414 (-)
C57BL/6NJ ENSMUSG00215030673
 protein coding gene Chr2:161826355-161949730 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024682
 protein coding gene Chr2:157060174-157184013 (-)
CAST/EiJ ENSTCUG00005044317
 protein coding gene Chr2:160745432-160869116 (-)
CBA/J ENSMUSG00210039778
 protein coding gene Chr2:162309151-162432419 (-)
DBA/2J ENSMUSG00185046049
 protein coding gene Chr2:162046148-162169526 (-)
FVB/NJ ENSMUSG00205037629
 protein coding gene Chr2:161067085-161190481 (-)
JF1/MsJ ENSUMUG00000006429
 protein coding gene Chr2:161691629-161815416 (-)
LP/J ENSMUSG00230009067
 protein coding gene Chr2:163603377-163726998 (-)
NOD/ShiLtJ ENSMUSG00190035729
 protein coding gene Chr2:161714055-161837333 (-)
NZO/HlLtJ ENSMUSG00225050747
 protein coding gene Chr2:171608492-171731856 (-)
PWK/PhJ ENSLUMG00010039589
 protein coding gene Chr2:161587609-161711350 (-)
SPRET/EiJ ENSMSPG00010023324
 protein coding gene Chr2:164349479-164419085 (-)
WSB/EiJ ENSIUOG00005040231
 protein coding gene Chr2:161440360-161563529 (-)



Homology
more
  • Human Ortholog
    CDH22, cadherin 22
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDH22, cadherin 22
  • Synonyms
    C20orf25, dJ998H6.1
  • Links
    NCBI Gene ID: 64405
    UniProt: Q9UJ99

  • Chr Location
    20q13.12; chr20:46173737-46309009 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    832
  • Tissues
    148
  • cDNA Data
    18
  • Literature Summary
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053166 Ensembl Gene Model | MGI Sequence Detail 123347 C57BL/6J ±  kb
transcript ENSMUST00000065438 Ensembl | MGI Sequence Detail 3702 Not Applicable  
polypeptide ENSMUSP00000066864 Ensembl | MGI Sequence Detail 813 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    Genomic 2
    cDNA 18
    Primer pair 4
    Other 2

    Microarray probesets 2
References
more
  • Summaries
    All 49
    Developmental Gene Expression 15
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:56108 Kitajima K, et al., Expression of a novel type of classic cadherin, PB-cadherin in developing brain and limb buds. Dev Dyn. 1999 Jul;215(3):206-14
  • Latest
    J:340669 Choi JS, et al., Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly. Cell Rep. 2023 Aug 24;42(9):113037
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory