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Myom1 Gene Detail
Summary
  • Symbol
    Myom1
  • Name
    myomesin 1
  • Synonyms
    D430047A17Rik, skelemin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341430
    NCBI Gene: 17929
  • Alliance
    genome feature page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:71326455-71433851 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 41.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3992 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341430
 protein coding gene Chr17:71309628-71433851 (+)
129S1/SvImJ ENSMUSG00200038754
 protein coding gene Chr17:66644657-66764857 (+)
A/J ENSMUSG00195016026
 protein coding gene Chr17:67990137-68113013 (+)
AKR/J ENSMUSG00220018014
 protein coding gene Chr17:67024721-67148326 (+)
BALB/cJ ENSMUSG00180019665
 protein coding gene Chr17:67726326-67849198 (+)
C3H/HeJ ENSMUSG00175027396
 protein coding gene Chr17:67039493-67162362 (+)
C57BL/6NJ ENSMUSG00215026947
 protein coding gene Chr17:66725709-66849945 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021854
 protein coding gene Chr17:66983724-67095761 (+)
CAST/EiJ ENSTCUG00005024178
 protein coding gene Chr17:67576653-67696008 (+)
CBA/J ENSMUSG00210028395
 protein coding gene Chr17:66851530-66974404 (+)
DBA/2J ENSMUSG00185022366
 protein coding gene Chr17:69684616-69807365 (+)
FVB/NJ ENSMUSG00205013972
 protein coding gene Chr17:67498907-67622529 (+)
JF1/MsJ ENSUMUG00000021408
 protein coding gene Chr17:69345415-69473828 (+)
LP/J ENSMUSG00230013248
 protein coding gene Chr17:70650025-70770094 (+)
NOD/ShiLtJ ENSMUSG00190024424
 protein coding gene Chr17:66787756-66911353 (+)
NZO/HlLtJ ENSMUSG00225028832
 protein coding gene Chr17:72923325-73046255 (+)
PWK/PhJ ENSLUMG00010028857
 protein coding gene Chr17:66567900-66698130 (+)
SPRET/EiJ ENSMSPG00010016067
 protein coding gene Chr17:66951494-67059594 (+)
WSB/EiJ ENSIUOG00005030513
 protein coding gene Chr17:67701680-67827996 (+)



Homology
more
  • Human Ortholog
    MYOM1, myomesin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYOM1, myomesin 1
  • Synonyms
    SKELEMIN
  • Links
    NCBI Gene ID: 8736
    UniProt: P52179

  • Chr Location
    18p11.31; chr18:3066693-3247376 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    795
  • Tissues
    125
  • cDNA Data
    24
  • Literature Summary
    35
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17929 NCBI Gene Model | MGI Sequence Detail 107397 C57BL/6J ±  kb
transcript NM_010867 RefSeq | MGI Sequence Detail 5579 C57BL/6  
polypeptide Q62234 UniProt | EBI | MGI Sequence Detail 1667 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    Genomic 6
    cDNA 24
    Primer pair 4
    Other 1
    Antibodies 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:2444174
References
more
  • Summaries
    All 71
    Developmental Gene Expression 35
    Gene Ontology 14
    Phenotypes 5
  • Earliest
    J:51749 Price MG, et al., Skelemin, a cytoskeletal M-disc periphery protein, contains motifs of adhesion/recognition and intermediate filament proteins. J Biol Chem. 1993 Oct 15;268(29):21800-10
  • Latest
    J:372759 Wu T, et al., RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing. Circ Res. 2025 Sep 12;137(7):1027-1044
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory