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Col14a1 Gene Detail
Summary
  • Symbol
    Col14a1
  • Name
    collagen, type XIV, alpha 1
  • Synonyms
    5730412L22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341272
    NCBI Gene: 12818
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:55171146-55384199 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 21.96 cM, cytoband D
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6737 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341272
 protein coding gene Chr15:55171040-55384199 (+)
129S1/SvImJ ENSMUSG00200027744
 protein coding gene Chr15:52153565-52359624 (+)
A/J ENSMUSG00195006002
 protein coding gene Chr15:52191397-52397565 (+)
AKR/J ENSMUSG00220019970
 protein coding gene Chr15:52198960-52405153 (+)
BALB/cJ ENSMUSG00180009018
 protein coding gene Chr15:52136686-52342833 (+)
C3H/HeJ ENSMUSG00175004512
 protein coding gene Chr15:52395255-52601382 (+)
C57BL/6NJ ENSMUSG00215010099
 protein coding gene Chr15:52134579-52340698 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019798
 protein coding gene Chr15:49469509-49678739 (+)
CAST/EiJ ENSTCUG00005006792
 protein coding gene Chr15:52023801-52231655 (+)
CBA/J ENSMUSG00210006821
 protein coding gene Chr15:52222440-52428590 (+)
DBA/2J ENSMUSG00185026320
 protein coding gene Chr15:52199933-52406105 (+)
FVB/NJ ENSMUSG00205006552
 protein coding gene Chr15:52045462-52251630 (+)
JF1/MsJ ENSUMUG00000018018
 protein coding gene Chr15:52032326-52239313 (+)
LP/J ENSMUSG00230007523
 protein coding gene Chr15:55515073-55721109 (+)
NOD/ShiLtJ ENSMUSG00190016205
 protein coding gene Chr15:52195915-52402056 (+)
NZO/HlLtJ ENSMUSG00225028108
 protein coding gene Chr15:55842138-56048240 (+)
PWK/PhJ ENSLUMG00010026783
 protein coding gene Chr15:52260090-52469804 (+)
SPRET/EiJ ENSMSPG00010022447
 protein coding gene Chr15:53338748-53547457 (+)
WSB/EiJ ENSIUOG00005006282
 protein coding gene Chr15:52221801-52427916 (+)



Homology
more
  • Human Ortholog
    COL14A1, collagen type XIV alpha 1 chain
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COL14A1, collagen type XIV alpha 1 chain
  • Synonyms
    UND
  • Links
    NCBI Gene ID: 7373
    UniProt: Q05707

  • Chr Location
    8q24.12; chr8:120059780-120373573 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COL14A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    2 images
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display abnormal tendon morphology and abnormal biomechanical properties of the skin and tendons.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    885
  • Tissues
    113
  • cDNA Data
    61
  • Literature Summary
    29
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022371 Ensembl Gene Model | MGI Sequence Detail 213054 C57BL/6J ±  kb
    transcript ENSMUST00000023053 Ensembl | MGI Sequence Detail 6457 Not Applicable  
    polypeptide ENSMUSP00000023053 Ensembl | MGI Sequence Detail 1797 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000005698 collagen alpha-1(XIV) chain
      (term hierarchy)
    • InterPro Domains
      IPR008160 Collagen triple helix repeat
      IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
      IPR050525 Extracellular Matrix Assembly and Organization
      IPR003961 Fibronectin type III
      IPR036116 Fibronectin type III superfamily
      IPR013783 Immunoglobulin-like fold
      IPR048287 Thrombospondin-like, N-terminal domain
      IPR036465 von Willebrand factor A-like domain superfamily
      IPR002035 von Willebrand factor, type A
    • GlyGen
      Q80X19 10 sites, 3 N-linked glycans (3 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 71
      cDNA 62
      Primer pair 7
      Other 2
      Antibodies 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1917736, MGI:2146190
    References
    more
    • Summaries
      All 78
      Developmental Gene Expression 29
      Diseases 1
      Gene Ontology 7
      Phenotypes 22
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:346374 Ushiki A, et al., Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality. Cell Rep. 2024 Mar 8;43(3):113907
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory