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S100a3 Gene Detail
Summary
  • Symbol
    S100a3
  • Name
    S100 calcium binding protein A3
  • Synonyms
    S100E
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338849
    NCBI Gene: 20197
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:90491966-90510009 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 39.26 cM, cytoband F1-F2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    591 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338849
 protein coding gene Chr3:90467571-90510922 (+)
129S1/SvImJ ENSMUSG00200037310
 protein coding gene Chr3:87348225-87366267 (+)
A/J ENSMUSG00195052314
 protein coding gene Chr3:87363429-87381474 (+)
AKR/J ENSMUSG00220044252
 protein coding gene Chr3:87326932-87344977 (+)
BALB/cJ ENSMUSG00180040275
 protein coding gene Chr3:87460944-87479174 (+)
C3H/HeJ ENSMUSG00175042267
 protein coding gene Chr3:87295921-87313966 (+)
C57BL/6NJ ENSMUSG00215049621
 protein coding gene Chr3:87735985-87754035 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025244
 protein coding gene Chr3:83355126-83401434 (+)
CAST/EiJ ENSTCUG00005045049
 protein coding gene Chr3:86821790-86839937 (+)
CBA/J ENSMUSG00210047246
 protein coding gene Chr3:87433598-87451640 (+)
DBA/2J ENSMUSG00185051088
 protein coding gene Chr3:87547376-87565404 (+)
FVB/NJ ENSMUSG00205035393
 protein coding gene Chr3:86357191-86375236 (+)
JF1/MsJ ENSUMUG00000049952
 protein coding gene Chr3:87162742-87180983 (+)
LP/J ENSMUSG00230035131
 protein coding gene Chr3:89569432-89587475 (+)
NOD/ShiLtJ ENSMUSG00190033132
 protein coding gene Chr3:87836632-87854702 (+)
NZO/HlLtJ ENSMUSG00225009532
 protein coding gene Chr3:92331407-92349434 (+)
PWK/PhJ ENSLUMG00010042830
 protein coding gene Chr3:87196841-87215100 (+)
SPRET/EiJ ENSMSPG00010049461
 protein coding gene Chr3:88075958-88094783 (+)
WSB/EiJ ENSIUOG00005049155
 protein coding gene Chr3:87851829-87869841 (+)



Homology
more
  • Human Ortholog
    S100A3, S100 calcium binding protein A3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    S100A3, S100 calcium binding protein A3
  • Synonyms
    S100E
  • Links
    NCBI Gene ID: 6274
    UniProt: P33764

  • Chr Location
    1q21.3; chr1:153547329-153550151 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    1
  • cDNA Data
    66
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000001021 Ensembl Gene Model | MGI Sequence Detail 18044 C57BL/6J ±  kb
    transcript ENSMUST00000200508 Ensembl | MGI Sequence Detail 587 Not Applicable  
    polypeptide ENSMUSP00000142747 Ensembl | MGI Sequence Detail 101 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 67
      Genomic 1
      cDNA 66

      Microarray probesets 4
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:50719 Kizawa K, et al., Gene expression of mouse S100A3, a cysteine-rich calcium-binding protein, in developing hair follicle. J Invest Dermatol. 1998 Nov;111(5):879-86
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory