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Spmap2 Gene Detail
Summary
  • Symbol
    Spmap2
  • Name
    sperm microtubule associated protein 2
  • Synonyms
    Theg
  • Feature Type
    protein coding gene
  • IDs
    MGI:1338756
    NCBI Gene: 21830
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79412311-79422970 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband B5-C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1338756
 protein coding gene Chr10:79412213-79423165 (-)
129S1/SvImJ ENSMUSG00200049750
 protein coding gene Chr10:76035459-76046409 (-)
A/J ENSMUSG00195037722
 protein coding gene Chr10:76430948-76441910 (-)
AKR/J ENSMUSG00220045378
 protein coding gene Chr10:76028518-76039472 (-)
BALB/cJ ENSMUSG00180045537
 protein coding gene Chr10:76441452-76452410 (-)
C3H/HeJ ENSMUSG00175047216
 protein coding gene Chr10:76312140-76323092 (-)
C57BL/6NJ ENSMUSG00215052565
 protein coding gene Chr10:76053833-76064788 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015528
 protein coding gene Chr10:73553171-73564080 (-)
CAST/EiJ ENSTCUG00005048099
 protein coding gene Chr10:75938881-75949874 (-)
CBA/J ENSMUSG00210048164
 protein coding gene Chr10:76168230-76179185 (-)
DBA/2J ENSMUSG00185050873
 protein coding gene Chr10:76510613-76521571 (-)
FVB/NJ ENSMUSG00205046098
 protein coding gene Chr10:76223381-76234342 (-)
JF1/MsJ ENSUMUG00000050699
 protein coding gene Chr10:77740992-77751999 (-)
LP/J ENSMUSG00230046472
 protein coding gene Chr10:78280388-78291340 (-)
NOD/ShiLtJ ENSMUSG00190038972
 protein coding gene Chr10:76424448-76435406 (-)
NZO/HlLtJ ENSMUSG00225050625
 protein coding gene Chr10:82566859-82577811 (-)
PWK/PhJ ENSLUMG00010050367
 protein coding gene Chr10:76100096-76111056 (-)
SPRET/EiJ ENSMSPG00010044559
 protein coding gene Chr10:77723152-77732056 (-)
WSB/EiJ ENSIUOG00005051053
 protein coding gene Chr10:76128011-76138926 (-)



Homology
more
  • Human Ortholog
    SPMAP2, sperm microtubule associated protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPMAP2, sperm microtubule associated protein 2
  • Synonyms
    CT56, THEG, THEG1
  • Links
    NCBI Gene ID: 51298
    UniProt: Q9P2T0

  • Chr Location
    19p13.3; chr19:361747-376026 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 3 genetic backgrounds
    11 phenotypes from multigenic genotypes
    1 images
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males homozygotes for a transgenic insertional mutation are sterile due to a block in spermiogenesis. Testis weights are reduced, and mutants exhibit multiple abnormalities in elongated spermatids in the seminiferous tubule lumen.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    5
  • cDNA Data
    7
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21830 NCBI Gene Model | MGI Sequence Detail 10660 C57BL/6J ±  kb
    transcript NM_011583 RefSeq | MGI Sequence Detail 1238 C57BL/6  
    polypeptide Q9JMB1 UniProt | EBI | MGI Sequence Detail 375 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:7470733
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory