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Wiz Gene Detail
Summary
  • Symbol
    Wiz
  • Name
    widely-interspaced zinc finger motifs
  • Feature Type
    protein coding gene
  • IDs
    MGI:1332638
    NCBI Gene: 22404
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:32573029-32608413 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.52 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    469 from dbSNP Build 142
  • Strain Annotations
    28
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1332638
 protein coding gene Chr17:32573021-32608463 (-)
129S1/SvImJ ENSMUSGG00200055004
 protein coding gene Chr17:28254580-28273084 (-)
129S1/SvImJ ENSMUSG00200052672
 protein coding gene Chr17:28272806-28281784 (-)
A/J ENSMUSGG00195055546
 protein coding gene Chr17:29194100-29212604 (-)
A/J ENSMUSG00195054318
 protein coding gene Chr17:29221052-29221296 (-)
AKR/J ENSMUSG00220049598
 protein coding gene Chr17:28240317-28249287 (-)
AKR/J ENSMUSGG00220054954
 protein coding gene Chr17:28222092-28239975 (-)
BALB/cJ ENSMUSG00180045103
 protein coding gene Chr17:28542991-28555885 (-)
C3H/HeJ ENSMUSGG00175055220
 protein coding gene Chr17:28103220-28121102 (-)
C3H/HeJ ENSMUSG00175051274
 protein coding gene Chr17:28130170-28130414 (-)
C57BL/6NJ ENSMUSG00215052643
 protein coding gene Chr17:28117816-28126792 (-)
C57BL/6NJ ENSMUSGG00215055847
 protein coding gene Chr17:28092488-28107123 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021382
 protein coding gene Chr17:28231453-28259821 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210047791
 protein coding gene Chr17:27948347-27957317 (-)
CBA/J ENSMUSGG00210055147
 protein coding gene Chr17:27930123-27948005 (-)
DBA/2J ENSMUSG00185053327
 protein coding gene Chr17:30567572-30567816 (-)
DBA/2J ENSMUSGG00185057998
 protein coding gene Chr17:30540613-30558496 (-)
FVB/NJ ENSMUSG00205048725
 protein coding gene Chr17:28444352-28453350 (-)
FVB/NJ ENSMUSGG00205054688
 protein coding gene Chr17:28426126-28444630 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230054222
 protein coding gene Chr17:31671319-31680296 (-)
LP/J ENSMUSGG00230055948
 protein coding gene Chr17:31653094-31670977 (-)
NOD/ShiLtJ ENSMUSGG00190055142
 protein coding gene Chr17:28052637-28071139 (-)
NOD/ShiLtJ ENSMUSG00190044657
 protein coding gene Chr17:28079598-28079842 (-)
NZO/HlLtJ ENSMUSG00225049795
 protein coding gene Chr17:33708293-33717270 (-)
NZO/HlLtJ ENSMUSGG00225055749
 protein coding gene Chr17:33690068-33707951 (-)
PWK/PhJ ENSLUMGG00010054396
 protein coding gene Chr17:27667634-27685340 (-)
SPRET/EiJ ENSMSPG00010040803
 protein coding gene Chr17:28797413-28825459 (-)
WSB/EiJ ENSIUOGG00005054470
 protein coding gene Chr17:28811546-28829253 (-)



Homology
more
  • Human Ortholog
    WIZ, WIZ zinc finger
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WIZ, WIZ zinc finger
  • Synonyms
    ZNF803
  • Links
    NCBI Gene ID: 58525
    UniProt: O95785

  • Chr Location
    19p13.12; chr19:15419978-15449975 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 3 alleles in 3 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice die prenatally.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    762
  • Tissues
    93
  • cDNA Data
    119
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024050 Ensembl Gene Model | MGI Sequence Detail 35385 C57BL/6J ±  kb
    transcript ENSMUST00000236409 Ensembl | MGI Sequence Detail 5058 Not Applicable  
    polypeptide ENSMUSP00000158082 Ensembl | MGI Sequence Detail 1685 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 125
      cDNA 120
      Primer pair 4
      Other 1
      Antibodies 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 7
      Gene Ontology 5
      Phenotypes 14
    • Earliest
      J:50534 Funke B, et al., Isolation and characterization of a human gene containing a nuclear localization signal from the critical region for velo-cardio-facial syndrome on 22q11. Genomics. 1998 Oct 15;53(2):146-54
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory