About   Help   FAQ
Cd83 Gene Detail
Summary
  • Symbol
    Cd83
  • Name
    CD83 antigen
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328316
    NCBI Gene: 12522
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:43938661-43956608 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 21.60 cM, cytoband A4-5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    571 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328316
 protein coding gene Chr13:43938251-43956608 (+)
129S1/SvImJ ENSMUSG00200035024
 protein coding gene Chr13:41203530-41221903 (+)
A/J ENSMUSG00195030734
 protein coding gene Chr13:40263484-40281853 (+)
AKR/J ENSMUSG00220028779
 protein coding gene Chr13:40053121-40071482 (+)
BALB/cJ ENSMUSG00180007850
 protein coding gene Chr13:40570133-40588500 (+)
C3H/HeJ ENSMUSG00175027750
 protein coding gene Chr13:40534552-40552917 (+)
C57BL/6NJ ENSMUSG00215004838
 protein coding gene Chr13:40681024-40699383 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018473
 protein coding gene Chr13:39052613-39071003 (+)
CAST/EiJ ENSTCUG00005029086
 protein coding gene Chr13:40591864-40610373 (+)
CBA/J ENSMUSG00210027386
 protein coding gene Chr13:40540145-40558514 (+)
DBA/2J ENSMUSG00185029942
 protein coding gene Chr13:41336289-41354646 (+)
FVB/NJ ENSMUSG00205010340
 protein coding gene Chr13:40292005-40310376 (+)
JF1/MsJ ENSUMUG00000009690
 protein coding gene Chr13:40883160-40901690 (+)
LP/J ENSMUSG00230024955
 protein coding gene Chr13:50672497-50690864 (+)
NOD/ShiLtJ ENSMUSG00190011370
 protein coding gene Chr13:40735180-40753545 (+)
NZO/HlLtJ ENSMUSG00225035918
 protein coding gene Chr13:44441459-44459809 (+)
PWK/PhJ ENSLUMG00010026179
 protein coding gene Chr13:39727723-39746082 (+)
SPRET/EiJ ENSMSPG00010010498
 protein coding gene Chr13:39792237-39809858 (+)
WSB/EiJ ENSIUOG00005027525
 protein coding gene Chr13:39875533-39893937 (+)



Homology
more
  • Human Ortholog
    CD83, CD83 molecule
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD83, CD83 molecule
  • Synonyms
    BL11, HB15
  • Links
    NCBI Gene ID: 9308
    UniProt: Q01151

  • Chr Location
    6p23; chr6:14117256-14140682 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 6 alleles in 6 genetic backgrounds
    2 phenotypes from multigenic genotypes
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice lacking this gene develop, thrive, and reproduce normally, but exhibit defects in T cell development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    649
  • Tissues
    36
  • cDNA Data
    41
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12522 NCBI Gene Model | MGI Sequence Detail 17948 C57BL/6J ±  kb
    transcript NM_009856 RefSeq | MGI Sequence Detail 2067 ZRU/MplStud  
    polypeptide O88324 UniProt | EBI | MGI Sequence Detail 196 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 50
      Genomic 3
      cDNA 41
      Primer pair 3
      Other 3

      Microarray probesets 4
    References
    more
    • Summaries
      All 73
      Developmental Gene Expression 8
      Gene Ontology 4
      Phenotypes 32
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory