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Vamp3 Gene Detail
Summary
  • Symbol
    Vamp3
  • Name
    vesicle-associated membrane protein 3
  • Synonyms
    ceb, cellubrevin, D130027G05Rik, VAMP-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1321389
    NCBI Gene: 22319
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:151131762-151142410 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 81.53 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    267 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1321389
 protein coding gene Chr4:151131757-151142420 (-)
129S1/SvImJ ENSMUSG00200018873
 protein coding gene Chr4:142194429-142205207 (-)
A/J ENSMUSG00195014746
 protein coding gene Chr4:143830950-143841603 (-)
AKR/J ENSMUSG00220023729
 protein coding gene Chr4:143416516-143427169 (-)
BALB/cJ ENSMUSG00180002268
 protein coding gene Chr4:141513490-141524143 (-)
C3H/HeJ ENSMUSG00175017316
 protein coding gene Chr4:144796796-144807449 (-)
C57BL/6NJ ENSMUSG00215007285
 protein coding gene Chr4:143641961-143652614 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026838
 protein coding gene Chr4:140939267-140949706 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210004617
 protein coding gene Chr4:143448420-143459073 (-)
DBA/2J ENSMUSG00185014035
 protein coding gene Chr4:147014425-147025205 (-)
FVB/NJ ENSMUSG00205037646
 protein coding gene Chr4:141910862-141921640 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230019687
 protein coding gene Chr4:153746466-153757246 (-)
NOD/ShiLtJ ENSMUSG00190003879
 protein coding gene Chr4:143114166-143124819 (-)
NZO/HlLtJ ENSMUSG00225023671
 protein coding gene Chr4:157741744-157752397 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    VAMP3, vesicle associated membrane protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VAMP3, vesicle associated membrane protein 3
  • Synonyms
    CEB
  • Links
    NCBI Gene ID: 9341
    UniProt: Q15836

  • Chr Location
    1p36.23; chr1:7771296-7781432 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 4 genetic backgrounds
    3 phenotypes from multigenic genotypes
    36 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for a targeted null mutation lack vesicle-associated membrane protein 3 but are apparently normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    53
  • GO References
    19
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    611
  • Tissues
    9
  • cDNA Data
    13
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22319 NCBI Gene Model | MGI Sequence Detail 10649 C57BL/6J ±  kb
    transcript NM_009498 RefSeq | MGI Sequence Detail 2115 C57BL/6  
    polypeptide P63024 UniProt | EBI | MGI Sequence Detail 103 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13
      Antibodies 3

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2444833
    References
    more
    • Summaries
      All 97
      Developmental Gene Expression 7
      Gene Ontology 19
      Phenotypes 36
    • Earliest
      J:34570 Martin S, et al., The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells. J Cell Biol. 1996 Aug;134(3):625-35
    • Latest
      J:385548 Coenen DM, et al., Platelet alpha-granule cargo packaging and endocytosis are important for normal mouse skin wound healing. Blood Adv. 2026 Jan 16;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory