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Rpl21 Gene Detail
Summary
  • Symbol
    Rpl21
  • Name
    ribosomal protein L21
  • Synonyms
    8430440E03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1278340
    NCBI Gene: 19933
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:146769955-146773842 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 86.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    305 from dbSNP Build 142
  • Strain Annotations
    23
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1278340
 protein coding gene Chr5:146769700-146773842 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J ENSMUSG00220037591
 protein coding gene ChrX:30489623-30490205 (+)
AKR/J ENSMUSG00220029396
 protein coding gene ChrX:123803167-123803727 (-)
AKR/J ENSMUSG00220022770
 protein coding gene Chr5:139215736-139219898 (+)
BALB/cJ ENSMUSG00180030951
 protein coding gene ChrX:31331070-31331707 (+)
BALB/cJ ENSMUSG00180026331
 protein coding gene Chr5:140591900-140594699 (+)
BALB/cJ ENSMUSG00180030202
 protein coding gene Chr5:99976246-99976807 (+)
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215016302
 protein coding gene ChrX:127477534-127478092 (-)
C57BL/6NJ ENSMUSG00215038350
 protein coding gene Chr5:140159045-140163187 (+)
C57BL/6NJ ENSMUSG00215046450
 protein coding gene ChrX:31364025-31364606 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028029
 protein coding gene Chr5:140407321-140411319 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J ENSMUSG00185047011
 protein coding gene Chr5:103685972-103686562 (+)
DBA/2J ENSMUSG00185032003
 protein coding gene ChrX:42313337-42313897 (+)
DBA/2J ENSMUSG00185038534
 protein coding gene Chr5:144320912-144323711 (+)
FVB/NJ ENSMUSG00205024063
 protein coding gene ChrX:127761002-127761553 (-)
FVB/NJ ENSMUSG00205035801
 protein coding gene Chr5:139970004-139974146 (+)
FVB/NJ ENSMUSG00205027543
 protein coding gene Chr5:97215947-97216550 (-)
JF1/MsJ no annotation
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190026737
 protein coding gene ChrX:30766586-30767655 (+)
NOD/ShiLtJ ENSMUSG00190041931
 protein coding gene Chr5:139963560-139966359 (+)
NZO/HlLtJ ENSMUSG00225042993
 protein coding gene ChrX:54046496-54047056 (+)
NZO/HlLtJ ENSMUSG00225007824
 protein coding gene Chr5:156065993-156070155 (+)
NZO/HlLtJ ENSMUSG00225042032
 protein coding gene ChrX:154310212-154310772 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010005734
 protein coding gene Chr5:141854083-141857622 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RPL21, ribosomal protein L21
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPL21, ribosomal protein L21
  • Synonyms
    eL21, HYPT12, L21
  • Links
    NCBI Gene ID: 6144
    UniProt: P46778

  • Chr Location
    13q12.2; chr13:27251283-27259609 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RPL21 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    641
  • Tissues
    37
  • cDNA Data
    12
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19933 NCBI Gene Model | MGI Sequence Detail 3888 C57BL/6J ±  kb
transcript NM_001408989 RefSeq | MGI Sequence Detail 2042 C57BL/6  
polypeptide O09167 UniProt | EBI | MGI Sequence Detail 160 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 2
    cDNA 12
    Primer pair 1

    Microarray probesets 12
Other
Accession IDs
less
MGI:1914064
References
more
  • Summaries
    All 48
    Developmental Gene Expression 7
    Gene Ontology 13
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory