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Stac Gene Detail
Summary
  • Symbol
    Stac
  • Name
    src homology three (SH3) and cysteine rich domain
  • Feature Type
    protein coding gene
  • IDs
    MGI:1201400
    NCBI Gene: 20840
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:111390505-111519416 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 61.81 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4281 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1201400
 protein coding gene Chr9:111386476-111519673 (-)
129S1/SvImJ ENSMUSG00200039031
 protein coding gene Chr9:108480527-108615641 (-)
A/J ENSMUSG00195033185
 protein coding gene Chr9:107777556-107939717 (-)
AKR/J ENSMUSG00220022436
 protein coding gene Chr9:108113003-108248144 (-)
BALB/cJ ENSMUSG00180020553
 protein coding gene Chr9:108232221-108367337 (-)
C3H/HeJ ENSMUSG00175032593
 protein coding gene Chr9:108447987-108583091 (-)
C57BL/6NJ ENSMUSG00215036342
 protein coding gene Chr9:108328200-108457365 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032759
 protein coding gene Chr9:106843321-106966780 (-)
CAST/EiJ ENSTCUG00005023300
 protein coding gene Chr9:108142970-108266351 (-)
CBA/J ENSMUSG00210028786
 protein coding gene Chr9:108169805-108291662 (-)
DBA/2J ENSMUSG00185035408
 protein coding gene Chr9:108495908-108631030 (-)
FVB/NJ ENSMUSG00205043936
 protein coding gene Chr9:108444043-108583489 (-)
JF1/MsJ ENSUMUG00000041100
 protein coding gene Chr9:108270997-108392934 (-)
LP/J ENSMUSG00230043581
 protein coding gene Chr9:108612592-108747685 (-)
NOD/ShiLtJ ENSMUSG00190047971
 protein coding gene Chr9:108083601-108218680 (-)
NZO/HlLtJ ENSMUSG00225023325
 protein coding gene Chr9:108866111-109001221 (-)
PWK/PhJ ENSLUMG00010027244
 protein coding gene Chr9:108282955-108405645 (-)
SPRET/EiJ ENSMSPG00010046558
 protein coding gene Chr9:110067567-110194580 (-)
WSB/EiJ ENSIUOG00005043738
 protein coding gene Chr9:107551499-107681012 (-)



Homology
more
  • Human Ortholog
    STAC, SH3 and cysteine rich domain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STAC, SH3 and cysteine rich domain
  • Synonyms
    STAC1
  • Links
    NCBI Gene ID: 6769
    UniProt: Q99469

  • Chr Location
    3p22.3-p22.2; chr3:36380321-36548045 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    647
  • Tissues
    27
  • cDNA Data
    9
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032502 Ensembl Gene Model | MGI Sequence Detail 128912 C57BL/6J ±  kb
transcript ENSMUST00000035083 Ensembl | MGI Sequence Detail 2644 Not Applicable  
polypeptide ENSMUSP00000035083 Ensembl | MGI Sequence Detail 403 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:42308 Suzuki H, et al., Stac, a novel neuron-specific protein with cysteine-rich and SH3 domains. Biochem Biophys Res Commun. 1996 Dec 24;229(3):902-9
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory