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Mrpl23 Gene Detail
Summary
  • Symbol
    Mrpl23
  • Name
    mitochondrial ribosomal protein L23
  • Synonyms
    L23mrp, Rpl23l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196612
    NCBI Gene: 19935
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:142086423-142094484 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 87.95 cM
  • Mapping Data
    15 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196612
 protein coding gene Chr7:142086423-142094484 (+)
129S1/SvImJ ENSMUSG00200044713
 protein coding gene Chr7:128645839-128661301 (+)
A/J ENSMUSG00195038277
 protein coding gene Chr7:133135176-133143353 (+)
AKR/J ENSMUSG00220034579
 protein coding gene Chr7:126610120-126625579 (+)
BALB/cJ ENSMUSG00180035147
 protein coding gene Chr7:129819344-129834805 (+)
C3H/HeJ ENSMUSG00175010591
 protein coding gene Chr2:71696562-71697170 (-)
C3H/HeJ ENSMUSG00175030045
 protein coding gene Chr7:130548822-130564281 (+)
C57BL/6NJ ENSMUSG00215045387
 protein coding gene Chr7:129815165-129830623 (+)
C57BL/6NJ ENSMUSG00215020029
 protein coding gene Chr2:71533502-71534126 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030727
 protein coding gene Chr7:144734280-144742048 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210026712
 protein coding gene Chr7:130306743-130322204 (+)
CBA/J ENSMUSG00210001886
 protein coding gene Chr2:71739203-71739811 (-)
DBA/2J ENSMUSG00185014609
 protein coding gene Chr7:134585328-134600786 (+)
DBA/2J ENSMUSG00185010160
 protein coding gene Chr2:71575051-71575660 (-)
FVB/NJ ENSMUSG00205044270
 protein coding gene Chr7:130227452-130242911 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230041560
 protein coding gene Chr7:140748663-140764120 (+)
NOD/ShiLtJ ENSMUSG00190020613
 protein coding gene Chr7:130414223-130429682 (+)
NZO/HlLtJ ENSMUSG00225014155
 protein coding gene Chr2:81133954-81134579 (-)
NZO/HlLtJ ENSMUSG00225051537
 protein coding gene Chr7:138957588-138973046 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MRPL23, mitochondrial ribosomal protein L23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL23, mitochondrial ribosomal protein L23
  • Synonyms
    L23MRP, L23mt, MRP-L23, RPL23L, uL23m
  • Links
    NCBI Gene ID: 6150
    UniProt: Q16540

  • Chr Location
    11p15.5; chr11:1947278-2014944 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    727
  • Tissues
    51
  • cDNA Data
    57
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19935 NCBI Gene Model | MGI Sequence Detail 8062 C57BL/6J ±  kb
transcript NM_001417208 RefSeq | MGI Sequence Detail 654 ZRU/MplStud  
polypeptide O35972 UniProt | EBI | MGI Sequence Detail 146 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    Genomic 16
    cDNA 58
    Primer pair 4

    Microarray probesets 4
References
more
  • Summaries
    All 65
    Developmental Gene Expression 5
    Gene Ontology 10
    Phenotypes 17
  • Earliest
    J:43998 Zubair M, et al., Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers. Genomics. 1997 Oct 15;45(2):290-6
  • Latest
    J:350560 Tomar A, et al., Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs. Nature. 2024 Jun;630(8017):720-727
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory