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Pira2 Gene Detail
Summary
  • Symbol
    Pira2
  • Name
    paired-Ig-like receptor A2
  • Synonyms
    6M23
Location &
Maps
more
  • Sequence Map
    Chr7:3839811-3848050 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    53 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1195970
 protein coding gene Chr7:3839807-3848102 (-)
129S1/SvImJ no annotation
A/J ENSMUSG00195048999
 protein coding gene Chr7:591231-599465 (-)
AKR/J ENSMUSG00220023626
 protein coding gene Chr7:3445429-3453670 (+)
BALB/cJ ENSMUSG00180046986
 protein coding gene Chr7:571652-579836 (-)
C3H/HeJ ENSMUSG00175045662
 protein coding gene Chr7:564035-572238 (-)
C57BL/6NJ ENSMUSG00215038193
 protein coding gene Chr7:557302-565551 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029101
 protein coding gene Chr7:592600-597565 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210037619
 protein coding gene Chr7:563962-572146 (-)
DBA/2J ENSMUSG00185041025
 protein coding gene Chr7:749418-757619 (-)
FVB/NJ ENSMUSG00205037220
 protein coding gene Chr7:567612-575813 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230033101
 protein coding gene Chr7:3771236-3779420 (-)
NOD/ShiLtJ ENSMUSG00190048369
 protein coding gene Chr7:591099-599331 (-)
NZO/HlLtJ ENSMUSG00225016883
 protein coding gene Chr7:1577494-1585753 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LILRA1, leukocyte immunoglobulin like receptor A1
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LILRA1, leukocyte immunoglobulin like receptor A1
  • Synonyms
    CD85I, LIR-6, LIR6
  • Links
    NCBI Gene ID: 11024
    UniProt: O75019

  • Chr Location
    19q13.42; chr19:54593582-54602381 (+)  GRCh38
  • Human Ortholog
    LILRA2, leukocyte immunoglobulin like receptor A2
  • Synonyms
    CD85H, ILT1, LIR-7, LIR7
  • Links
    NCBI Gene ID: 11027
    UniProt: Q8N149

  • Chr Location
    19q13.42; chr19:54572920-54590287 (+)  GRCh38
  • Human Ortholog
    LILRA4, leukocyte immunoglobulin like receptor A4
  • Synonyms
    CD85g, ILT7
  • Links
    NCBI Gene ID: 23547
    UniProt: P59901

  • Chr Location
    19q13.42; chr19:54333185-54339162 (-)  GRCh38
  • Human Ortholog
    LILRA6, leukocyte immunoglobulin like receptor A6
  • Synonyms
    CD85b, ILT5, ILT-8, ILT8, LILRB6
  • Links
    NCBI Gene ID: 79168
    UniProt: Q6PI73

  • Chr Location
    19q13.42; chr19:54236590-54242790 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000089942 Ensembl Gene Model | MGI Sequence Detail 8240 C57BL/6J ±  kb
transcript ENSMUST00000108615 Ensembl | MGI Sequence Detail 3462 Not Applicable  
polypeptide ENSMUSP00000104255 Ensembl | MGI Sequence Detail 680 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR003599 Immunoglobulin domain subtype
    IPR013151 Immunoglobulin-like beta-sandwich domain
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR050412 Immunoglobulin-like Receptors in Immune Regulation
    IPR003598 Immunoglobulin subtype 2
  • GlyGen
    F8VQ94 1 site
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Other 1
References
more
  • Summaries
    All 16
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:44191 Kubagawa H, et al., A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells [see comments]. Proc Natl Acad Sci U S A. 1997 May 13;94(10):5261-6
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory