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Ficd Gene Detail
Summary
  • Symbol
    Ficd
  • Name
    FIC domain containing
  • Synonyms
    D5Ertd40e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098550
    NCBI Gene: 231630
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:113873864-113878661 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 55.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    204 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098550
 protein coding gene Chr5:113873821-113878670 (+)
129S1/SvImJ ENSMUSG00200021514
 protein coding gene Chr5:107614541-107619336 (+)
A/J ENSMUSG00195032094
 protein coding gene Chr5:107124484-107129282 (+)
AKR/J ENSMUSG00220051144
 protein coding gene Chr5:106642855-106647652 (+)
BALB/cJ ENSMUSG00180045119
 protein coding gene Chr5:107265018-107269813 (+)
C3H/HeJ ENSMUSG00175046020
 protein coding gene Chr5:109245008-109249807 (+)
C57BL/6NJ ENSMUSG00215011275
 protein coding gene Chr5:107273876-107278673 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027579
 protein coding gene Chr5:106679687-106684567 (+)
CAST/EiJ ENSTCUG00005027771
 protein coding gene Chr5:106447616-106452442 (+)
CBA/J ENSMUSG00210041863
 protein coding gene Chr5:107997123-108001921 (+)
DBA/2J ENSMUSG00185043773
 protein coding gene Chr5:111049088-111053885 (+)
FVB/NJ ENSMUSG00205031301
 protein coding gene Chr5:106902718-106907513 (+)
JF1/MsJ ENSUMUG00000036171
 protein coding gene Chr5:113884634-113889458 (+)
LP/J ENSMUSG00230042941
 protein coding gene Chr5:115152759-115157554 (+)
NOD/ShiLtJ ENSMUSG00190046560
 protein coding gene Chr5:106941963-106946760 (+)
NZO/HlLtJ ENSMUSG00225015290
 protein coding gene Chr5:122798901-122803698 (+)
PWK/PhJ ENSLUMG00010027217
 protein coding gene Chr5:105788680-105793505 (+)
SPRET/EiJ ENSMSPG00010042246
 protein coding gene Chr5:109077217-109080743 (+)
WSB/EiJ ENSIUOG00005038649
 protein coding gene Chr5:109640579-109645375 (+)



Homology
more
  • Human Ortholog
    FICD, FIC domain protein adenylyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FICD, FIC domain protein adenylyltransferase
  • Synonyms
    HIP13, HYPE, SPG92, UNQ3041
  • Links
    NCBI Gene ID: 11153
    UniProt: Q9BVA6

  • Chr Location
    12q23.3; chr12:108513710-108525837 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human FICD associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    46
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    612
  • Tissues
    12
  • cDNA Data
    9
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000053334 Ensembl Gene Model | MGI Sequence Detail 4798 C57BL/6J ±  kb
    transcript ENSMUST00000065698 Ensembl | MGI Sequence Detail 3133 Not Applicable  
    polypeptide ENSMUSP00000071719 Ensembl | MGI Sequence Detail 458 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 14
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:391231 Casey AK, et al., Pre-clinical model of dysregulated FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis. Mol Metab. 2025 Mar 10;95:102120
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory