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Sp100 Gene Detail
Summary
  • Symbol
    Sp100
  • Name
    nuclear antigen Sp100
  • Synonyms
    A430075G10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:109561
    NCBI Gene: 20684
  • Alliance
    genome feature page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:85577709-85637719 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 43.60 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1053 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109561
 protein coding gene Chr1:85577683-85637719 (+)
129S1/SvImJ ENSMUSG00200036923
 protein coding gene Chr1:82794435-82854708 (+)
A/J ENSMUSG00195029552
 protein coding gene Chr1:82278069-82426943 (+)
AKR/J ENSMUSG00220037274
 protein coding gene Chr1:82488672-82548623 (+)
BALB/cJ ENSMUSG00180014525
 protein coding gene Chr1:82664644-82724937 (+)
C3H/HeJ ENSMUSG00175001065
 protein coding gene Chr1:82545618-82605836 (+)
C57BL/6NJ ENSMUSG00215011183
 protein coding gene Chr1:82466398-82526634 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014348
 protein coding gene Chr1:78112571-78172676 (+)
CAST/EiJ ENSTCUG00005007017
 protein coding gene Chr1:82117383-82178420 (+)
CBA/J ENSMUSG00210012313
 protein coding gene Chr1:82389100-82449014 (+)
DBA/2J ENSMUSG00185015290
 protein coding gene Chr1:86862123-86922382 (+)
FVB/NJ ENSMUSG00205032566
 protein coding gene Chr1:81801016-81861550 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230014847
 protein coding gene Chr1:86140435-86200681 (+)
NOD/ShiLtJ ENSMUSG00190020436
 protein coding gene Chr1:82444194-82504120 (+)
NZO/HlLtJ ENSMUSG00225004186
 protein coding gene Chr1:90043236-90103491 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010039804
 protein coding gene Chr1:84023209-84081869 (+)
WSB/EiJ ENSIUOG00005038594
 protein coding gene Chr1:82045364-82106011 (+)



Homology
more
  • Human Ortholog
    SP100, SP100 nuclear body protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SP100, SP100 nuclear body protein
  • Synonyms
    lysp100b
  • Links
    NCBI Gene ID: 6672
    UniProt: P23497

  • Chr Location
    2q37.1; chr2:230415942-230545606 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    50
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    114
  • cDNA Data
    35
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026222 Ensembl Gene Model | MGI Sequence Detail 60011 C57BL/6J ±  kb
transcript ENSMUST00000066427 Ensembl | MGI Sequence Detail 2708 Not Applicable  
polypeptide ENSMUSP00000066399 Ensembl | MGI Sequence Detail 591 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    Genomic 11
    cDNA 39

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-39560, MGI:2443000
References
more
  • Summaries
    All 46
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory