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Col16a1 Gene Detail
Summary
  • Symbol
    Col16a1
  • Name
    collagen, type XVI, alpha 1
  • Synonyms
    2700007F12Rik, [a]1 (XVI) collagen, A530052M23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1095396
    NCBI Gene: 107581
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129941638-129993070 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.43 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    567 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1095396
 protein coding gene Chr4:129941633-129993076 (+)
129S1/SvImJ ENSMUSG00200018921
 protein coding gene Chr4:123384936-123387194 (+)
A/J ENSMUSG00195038883
 protein coding gene Chr4:124718690-124720948 (+)
AKR/J ENSMUSG00220040198
 protein coding gene Chr4:123710463-123712719 (+)
BALB/cJ ENSMUSG00180039704
 protein coding gene Chr4:122352320-122354578 (+)
C3H/HeJ ENSMUSG00175037412
 protein coding gene Chr4:123364900-123367156 (+)
C57BL/6NJ ENSMUSGG00215055746
 protein coding gene Chr4:124873792-124877364 (+)
C57BL/6NJ ENSMUSG00215050593
 protein coding gene Chr4:124868384-124870629 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026538
 protein coding gene Chr4:119860511-119911996 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210052817
 protein coding gene Chr4:122993894-122996150 (+)
DBA/2J ENSMUSG00185048157
 protein coding gene Chr4:124526267-124528523 (+)
FVB/NJ ENSMUSG00205034046
 protein coding gene Chr4:122753090-122755344 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230031785
 protein coding gene Chr4:128320724-128372410 (+)
NOD/ShiLtJ ENSMUSG00190045905
 protein coding gene Chr4:122758724-122760982 (+)
NZO/HlLtJ ENSMUSG00225025979
 protein coding gene Chr4:134237167-134239423 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010040001
 protein coding gene Chr4:124278804-124329669 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    COL16A1, collagen type XVI alpha 1 chain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COL16A1, collagen type XVI alpha 1 chain
  • Synonyms
    447AA, FP1572
  • Links
    NCBI Gene ID: 1307
    UniProt: Q07092

  • Chr Location
    1p35.2; chr1:31652260-31704319 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    675
  • Tissues
    49
  • cDNA Data
    65
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 107581 NCBI Gene Model | MGI Sequence Detail 51433 C57BL/6J ±  kb
    transcript NM_001404352 RefSeq | MGI Sequence Detail 5225 C57BL/6  
    polypeptide Q8BLX7 UniProt | EBI | MGI Sequence Detail 1580 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 69
      cDNA 67
      Other 2
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1919771, MGI:2140369, MGI:2447869
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 11
      Gene Ontology 11
      Phenotypes 12
    • Earliest
      J:34846 Lai CH, et al., Tissue distribution and developmental expression of type XVI collagen in the mouse. Tissue Cell. 1996 Apr;28(2):155-64
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory