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Tsx Gene Detail
Summary
  • Symbol
    Tsx
  • Name
    testis specific X-linked gene
  • Feature Type
    protein coding gene
  • IDs
    MGI:108118
    NCBI Gene: 22127
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:102458073-102468186 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 46.12 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    239 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108118
 protein coding gene ChrX:102452618-102468194 (+)
129S1/SvImJ ENSMUSG00200037959
 protein coding gene ChrX:84222485-84232609 (+)
A/J ENSMUSG00195036371
 protein coding gene ChrX:87977201-87987323 (+)
AKR/J ENSMUSG00220033920
 protein coding gene ChrX:82644419-82654546 (+)
BALB/cJ ENSMUSG00180039081
 protein coding gene ChrX:84654468-84664593 (+)
C3H/HeJ ENSMUSG00175038147
 protein coding gene ChrX:88227334-88237458 (+)
C57BL/6NJ ENSMUSG00215045875
 protein coding gene ChrX:84834472-84844585 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033309
 protein coding gene ChrX:97638708-97648589 (+)
CAST/EiJ ENSTCUG00005039489
 protein coding gene ChrX:85699155-85709186 (+)
CBA/J ENSMUSG00210039124
 protein coding gene ChrX:85118082-85128207 (+)
DBA/2J ENSMUSG00185041398
 protein coding gene ChrX:97556918-97567045 (+)
FVB/NJ ENSMUSG00205030561
 protein coding gene ChrX:84199608-84209730 (+)
JF1/MsJ ENSUMUG00000032138
 protein coding gene ChrX:118165855-118175858 (+)
LP/J ENSMUSG00230039097
 protein coding gene ChrX:104255666-104265789 (+)
NOD/ShiLtJ ENSMUSG00190036472
 protein coding gene ChrX:84275960-84286084 (+)
NZO/HlLtJ ENSMUSG00225044752
 protein coding gene ChrX:109376057-109386177 (+)
PWK/PhJ ENSLUMG00010034013
 protein coding gene ChrX:83480982-83490935 (+)
SPRET/EiJ ENSMSPG00010037537
 protein coding gene ChrX:87687729-87697198 (+)
WSB/EiJ ENSIUOG00005038701
 protein coding gene ChrX:84779015-84789174 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Female mice homozygous for a knock-out allele exhibit reduced fertility and decreased litter size, while hemizygous males show smaller testis size, pachytene-stage spermatocyte apoptosis, and enhanced contextual conditioning behavior.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    5
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    606
  • Tissues
    2
  • cDNA Data
    7
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031329 Ensembl Gene Model | MGI Sequence Detail 10114 C57BL/6J ±  kb
    transcript ENSMUST00000033691 Ensembl | MGI Sequence Detail 812 Not Applicable  
    polypeptide ENSMUSP00000033691 Ensembl | MGI Sequence Detail 144 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      Genomic 10
      cDNA 7
      Other 1
      Antibodies 3

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-37155, MGI:2147981
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:36484 Simmler MC, et al., A 94 kb genomic sequence 3' to the murine Xist gene reveals an AT rich region containing a new testis specific gene Tsx. Hum Mol Genet. 1996 Nov;5(11):1713-26
    • Latest
      J:356411 Bao J, et al., Expression profiling reveals developmentally regulated lncRNA repertoire in the mouse male germline. Biol Reprod. 2013 Nov;89(5):107
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory