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Cited1 Gene Detail
Summary
  • Symbol
    Cited1
  • Name
    Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
  • Synonyms
    Msg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108023
    NCBI Gene: 12705
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:101290987-101295787 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 45.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    23
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108023
 protein coding gene ChrX:101290984-101295787 (-)
129S1/SvImJ ENSMUSG00200038053
 protein coding gene ChrX:83004624-83009425 (-)
A/J ENSMUSG00195034426
 protein coding gene Chr15:31294375-31295169 (-)
A/J ENSMUSG00195038743
 protein coding gene ChrX:86759469-86764271 (-)
AKR/J ENSMUSG00220028340
 protein coding gene Chr15:31197189-31197983 (-)
AKR/J ENSMUSG00220035972
 protein coding gene ChrX:81450285-81455086 (-)
BALB/cJ ENSMUSG00180041323
 protein coding gene ChrX:83469847-83474647 (-)
BALB/cJ ENSMUSG00180029403
 protein coding gene Chr15:31251022-31251821 (-)
C3H/HeJ ENSMUSG00175039094
 protein coding gene ChrX:87130213-87135013 (-)
C57BL/6NJ ENSMUSG00215045398
 protein coding gene ChrX:83660470-83665271 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033299
 protein coding gene ChrX:96494298-96499091 (-)
CAST/EiJ ENSTCUG00005039755
 protein coding gene ChrX:84514588-84519384 (-)
CBA/J ENSMUSG00210039404
 protein coding gene ChrX:83901017-83905818 (-)
DBA/2J ENSMUSG00185041166
 protein coding gene ChrX:96344040-96348840 (-)
FVB/NJ ENSMUSG00205019847
 protein coding gene Chr15:31252178-31252972 (-)
FVB/NJ ENSMUSG00205032357
 protein coding gene ChrX:83158769-83163572 (-)
JF1/MsJ ENSUMUG00000019591
 protein coding gene ChrX:116937553-116942347 (-)
LP/J ENSMUSG00230039617
 protein coding gene ChrX:103038094-103042894 (-)
NOD/ShiLtJ ENSMUSG00190028015
 protein coding gene ChrX:83055865-83060666 (-)
NZO/HlLtJ ENSMUSG00225045102
 protein coding gene ChrX:108139445-108144246 (-)
PWK/PhJ ENSLUMG00010033372
 protein coding gene ChrX:82205880-82210668 (-)
SPRET/EiJ ENSMSPG00010038693
 protein coding gene ChrX:86499674-86504443 (-)
WSB/EiJ ENSIUOG00005038394
 protein coding gene ChrX:83582587-83587387 (-)



Homology
more
  • Human Ortholog
    CITED1, Cbp/p300 interacting transactivator with ED-rich tail 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CITED1, Cbp/p300 interacting transactivator with ED-rich tail 1
  • Synonyms
    MSG1
  • Links
    NCBI Gene ID: 4435
    UniProt: Q99966

  • Chr Location
    Xq13.1; chrX:72301638-72309652 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 2 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutation of this locus results in impaired embyronic growth and survival due to defects in trophoblast and placental development. Phenotypic penetrance is subject to influence by genetic background and parental inheritance.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    95
  • GO References
    18
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1354
  • Tissues
    306
  • cDNA Data
    60
  • Literature Summary
    101
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051159 Ensembl Gene Model | MGI Sequence Detail 4801 C57BL/6J ±  kb
    transcript ENSMUST00000050551 Ensembl | MGI Sequence Detail 901 Not Applicable  
    polypeptide ENSMUSP00000051789 Ensembl | MGI Sequence Detail 203 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 82
      Genomic 2
      cDNA 60
      Primer pair 11
      Other 9
      Antibodies 9

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-37059, MGI:2147868, MGI:2147960
    References
    more
    • Summaries
      All 162
      Developmental Gene Expression 101
      Gene Ontology 18
      Phenotypes 14
    • Earliest
      J:36248 Shioda T, et al., msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12298-303
    • Latest
      J:390120 Trowe MO, et al., Mesenchymal WNT signaling coordinates epithelial and mesenchymal differentiation in the developing murine ureter. Cell Commun Signal. 2026 Jul 21;24(1)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory