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Wnt8a Gene Detail
Summary
  • Symbol
    Wnt8a
  • Name
    wingless-type MMTV integration site family, member 8A
  • Synonyms
    Stra11
  • Feature Type
    protein coding gene
  • IDs
    MGI:107924
    NCBI Gene: 20890
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:34675380-34681114 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 18.69 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    221 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107924
 protein coding gene Chr18:34675366-34681326 (+)
129S1/SvImJ ENSMUSG00200043253
 protein coding gene Chr18:31673316-31679271 (+)
A/J ENSMUSG00195035048
 protein coding gene Chr18:31835849-31841802 (+)
AKR/J ENSMUSG00220016823
 protein coding gene Chr18:31816617-31822577 (+)
BALB/cJ ENSMUSG00180017729
 protein coding gene Chr18:32285530-32291483 (+)
C3H/HeJ ENSMUSG00175030551
 protein coding gene Chr18:31786505-31792457 (+)
C57BL/6NJ ENSMUSG00215025220
 protein coding gene Chr18:31543767-31549727 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022090
 protein coding gene Chr18:31798594-31804516 (+)
CAST/EiJ ENSTCUG00005023557
 protein coding gene Chr18:31440351-31446318 (+)
CBA/J ENSMUSG00210021367
 protein coding gene Chr18:31827699-31833652 (+)
DBA/2J ENSMUSG00185019922
 protein coding gene Chr18:31762286-31768239 (+)
FVB/NJ ENSMUSG00205025652
 protein coding gene Chr18:31483683-31489643 (+)
JF1/MsJ ENSUMUG00000041145
 protein coding gene Chr18:31904528-31910521 (+)
LP/J ENSMUSG00230045014
 protein coding gene Chr18:33870133-33876086 (+)
NOD/ShiLtJ ENSMUSG00190021038
 protein coding gene Chr18:31540276-31546228 (+)
NZO/HlLtJ ENSMUSG00225044471
 protein coding gene Chr18:33775391-33781351 (+)
PWK/PhJ ENSLUMG00010010690
 protein coding gene Chr18:32050129-32056124 (+)
SPRET/EiJ ENSMSPG00010019369
 protein coding gene Chr18:32108078-32113443 (+)
WSB/EiJ ENSIUOG00005007462
 protein coding gene Chr18:31541218-31547171 (+)



Homology
more
  • Human Ortholog
    WNT8A, Wnt family member 8A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WNT8A, Wnt family member 8A
  • Synonyms
    WNT8D
  • Links
    NCBI Gene ID: 7478
    UniProt: Q9H1J5

  • Chr Location
    5q31.2; chr5:138077367-138092365 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    6 phenotype references
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1273
  • Tissues
    512
  • cDNA Data
    14
  • Literature Summary
    71
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20890 NCBI Gene Model | MGI Sequence Detail 5735 C57BL/6J ±  kb
transcript NM_009290 RefSeq | MGI Sequence Detail 1520 C57BL/6  
polypeptide Q64527 UniProt | EBI | MGI Sequence Detail 354 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 16
    Primer pair 17
    Other 9

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36504
References
more
  • Summaries
    All 101
    Developmental Gene Expression 71
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:28316 Bouillet P, et al., Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). Dev Biol. 1995 Aug;170(2):420-33
  • Latest
    J:381062 Kyei-Barffour I, et al., Wnt5a Regulates Embryonic Mullerian Duct Development Through the Non-Canonical Wnt PCP Pathway. Cells. 2026 Feb 17;15(4)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory