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Tpd52 Gene Detail
Summary
  • Symbol
    Tpd52
  • Name
    tumor protein D52
  • Synonyms
    mD52
  • Feature Type
    protein coding gene
  • IDs
    MGI:107749
    NCBI Gene: 21985
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:8991590-9069824 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 2.23 cM, cytoband A1-A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2933 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107749
 protein coding gene Chr3:8990653-9069824 (-)
129S1/SvImJ ENSMUSG00200000691
 protein coding gene Chr3:5667043-5701495 (-)
129S1/SvImJ ENSMUSGG00200054936
 protein coding gene Chr3:5740725-5741923 (-)
A/J ENSMUSGG00195055319
 protein coding gene Chr3:6077462-6078660 (-)
A/J ENSMUSG00195001188
 protein coding gene Chr3:5998255-6032706 (-)
AKR/J ENSMUSG00220017045
 protein coding gene Chr3:6000498-6034788 (-)
AKR/J ENSMUSGG00220054705
 protein coding gene Chr3:6075491-6076689 (-)
BALB/cJ ENSMUSGG00180055389
 protein coding gene Chr3:6099813-6101011 (-)
BALB/cJ ENSMUSG00180006987
 protein coding gene Chr3:6015182-6055180 (-)
C3H/HeJ ENSMUSG00175005028
 protein coding gene Chr3:6006769-6041218 (-)
C3H/HeJ ENSMUSGG00175055011
 protein coding gene Chr3:6085845-6087043 (-)
C57BL/6NJ ENSMUSG00215005126
 protein coding gene Chr3:6023694-6058146 (-)
C57BL/6NJ ENSMUSGG00215055603
 protein coding gene Chr3:6097388-6098586 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024834
 protein coding gene Chr3:4997143-5081320 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210000550
 protein coding gene Chr3:5991935-6026385 (-)
CBA/J ENSMUSGG00210054879
 protein coding gene Chr3:6071011-6072209 (-)
DBA/2J ENSMUSGG00185057788
 protein coding gene Chr3:6077729-6078927 (-)
DBA/2J ENSMUSG00185000482
 protein coding gene Chr3:6004075-6038525 (-)
FVB/NJ ENSMUSG00205005802
 protein coding gene Chr3:5824558-5858849 (-)
FVB/NJ ENSMUSGG00205054413
 protein coding gene Chr3:5899557-5900755 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230000048
 protein coding gene Chr3:7919062-7953513 (-)
LP/J ENSMUSGG00230055722
 protein coding gene Chr3:7992745-7993943 (-)
NOD/ShiLtJ ENSMUSG00190022196
 protein coding gene Chr3:6093578-6127869 (-)
NOD/ShiLtJ ENSMUSGG00190054977
 protein coding gene Chr3:6168566-6169764 (-)
NZO/HlLtJ ENSMUSGG00225055407
 protein coding gene Chr3:10565963-10567161 (-)
NZO/HlLtJ ENSMUSG00225000449
 protein coding gene Chr3:10492265-10526717 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TPD52, tumor protein D52
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TPD52, tumor protein D52
  • Synonyms
    D52, hD52, N8L, PC-1, PrLZ
  • Links
    NCBI Gene ID: 7163
    UniProt: P55327

  • Chr Location
    8q21.13; chr8:80031082-80231232 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    879
  • Tissues
    53
  • cDNA Data
    221
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21985 NCBI Gene Model | MGI Sequence Detail 78235 C57BL/6J ±  kb
transcript NM_001357072 RefSeq | MGI Sequence Detail 5712 C57BL/6  
polypeptide Q62393 UniProt | EBI | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 223
    cDNA 222
    Other 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-36325, MGI:2139619
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:34618 Byrne JA, et al., Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52). Genomics. 1996 Aug 1;35(3):523-32
  • Latest
    J:243218 Hooper JE, et al., Systems biology of facial development: contributions of ectoderm and mesenchyme. Dev Biol. 2017 Jun 01;426(1):97-114
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory