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Mrpl50 Gene Detail
Summary
  • Symbol
    Mrpl50
  • Name
    mitochondrial ribosomal protein L50
  • Synonyms
    D4Wsu125e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107329
    NCBI Gene: 28028
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:49512597-49521083 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 26.54 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    269 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107329
 protein coding gene Chr4:49512596-49521093 (-)
129S1/SvImJ ENSMUSG00200002326
 protein coding gene Chr4:45590728-45599230 (-)
A/J ENSMUSG00195005442
 protein coding gene Chr4:46007996-46016493 (-)
AKR/J ENSMUSG00220002596
 protein coding gene Chr4:45732581-45741078 (-)
BALB/cJ ENSMUSG00180028989
 protein coding gene Chr4:45594655-45603152 (-)
C3H/HeJ ENSMUSG00175020975
 protein coding gene Chr4:45743553-45752050 (-)
C57BL/6NJ ENSMUSG00215021512
 protein coding gene Chr4:45541617-45550114 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026011
 protein coding gene Chr4:43420415-43428818 (-)
CAST/EiJ ENSTCUG00005033885
 protein coding gene Chr4:45858723-45867205 (-)
CBA/J ENSMUSG00210019444
 protein coding gene Chr4:45448519-45457016 (-)
DBA/2J ENSMUSG00185031538
 protein coding gene Chr4:45806989-45815486 (-)
FVB/NJ ENSMUSG00205015558
 protein coding gene Chr4:45099457-45107954 (-)
JF1/MsJ ENSUMUG00000024359
 protein coding gene Chr4:46098621-46107173 (-)
LP/J ENSMUSG00230037803
 protein coding gene Chr4:49386469-49394971 (-)
NOD/ShiLtJ ENSMUSG00190024946
 protein coding gene Chr4:45697593-45706090 (-)
NZO/HlLtJ ENSMUSG00225002629
 protein coding gene Chr4:53976686-53985183 (-)
PWK/PhJ ENSLUMG00010012101
 protein coding gene Chr4:45011705-45020249 (-)
SPRET/EiJ ENSMSPG00010008318
 protein coding gene Chr4:46064797-46071460 (-)
WSB/EiJ ENSIUOG00005004338
 protein coding gene Chr4:45429082-45437592 (-)



Homology
more
  • Human Ortholog
    MRPL50, mitochondrial ribosomal protein L50
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL50, mitochondrial ribosomal protein L50
  • Synonyms
    mL50, MRP-L50
  • Links
    NCBI Gene ID: 54534
    UniProt: Q8N5N7

  • Chr Location
    9q31.1; chr9:101387633-101398618 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    10
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    617
  • Tissues
    13
  • cDNA Data
    84
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 28028 NCBI Gene Model | MGI Sequence Detail 8487 C57BL/6J ±  kb
transcript NM_178603 RefSeq | MGI Sequence Detail 2103 ZRU/MplStud  
polypeptide Q8VDT9 UniProt | EBI | MGI Sequence Detail 159 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 86
    cDNA 84
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-35795, MGI:2140141, MGI:2140233
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 6
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory