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Txlna Gene Detail
Summary
  • Symbol
    Txlna
  • Name
    taxilin alpha
  • Synonyms
    2600010N21Rik, IL14, Txln
  • Feature Type
    protein coding gene
  • IDs
    MGI:105968
    NCBI Gene: 109658
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129519871-129534858 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.26 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    163 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105968
 protein coding gene Chr4:129519870-129534867 (-)
129S1/SvImJ ENSMUSG00200020131
 protein coding gene Chr4:122955899-122973218 (-)
A/J ENSMUSG00195036962
 protein coding gene Chr4:124291705-124308841 (-)
AKR/J ENSMUSG00220046074
 protein coding gene Chr4:123283237-123300373 (-)
BALB/cJ ENSMUSG00180048061
 protein coding gene Chr4:121925398-121942535 (-)
C3H/HeJ ENSMUSG00175044514
 protein coding gene Chr4:122938008-122955144 (-)
C57BL/6NJ ENSMUSG00215051442
 protein coding gene Chr4:124441854-124459164 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026531
 protein coding gene Chr4:119433601-119448861 (-)
CAST/EiJ ENSTCUG00005043664
 protein coding gene Chr4:123822368-123839509 (-)
CBA/J ENSMUSG00210053637
 protein coding gene Chr4:122567021-122584157 (-)
DBA/2J ENSMUSG00185051812
 protein coding gene Chr4:124099369-124116505 (-)
FVB/NJ ENSMUSG00205039470
 protein coding gene Chr4:122325231-122343090 (-)
JF1/MsJ ENSUMUG00000029796
 protein coding gene Chr4:124744878-124762218 (-)
LP/J ENSMUSG00230033089
 protein coding gene Chr4:127893338-127910656 (-)
NOD/ShiLtJ ENSMUSG00190043700
 protein coding gene Chr4:122330831-122347961 (-)
NZO/HlLtJ ENSMUSG00225024580
 protein coding gene Chr4:133810282-133827418 (-)
PWK/PhJ ENSLUMG00010045629
 protein coding gene Chr4:121782788-121800204 (-)
SPRET/EiJ ENSMSPG00010044151
 protein coding gene Chr4:123854635-123869178 (-)
WSB/EiJ ENSIUOG00005041816
 protein coding gene Chr4:122191816-122209134 (-)



Homology
more
  • Human Ortholog
    TXLNA, taxilin alpha
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TXLNA, taxilin alpha
  • Synonyms
    IL-14, IL14, TXLN
  • Links
    NCBI Gene ID: 200081
    UniProt: P40222

  • Chr Location
    1p35.2; chr1:32178097-32198299 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    5
  • cDNA Data
    213
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000053841 Ensembl Gene Model | MGI Sequence Detail 14988 C57BL/6J ±  kb
    transcript ENSMUST00000046425 Ensembl | MGI Sequence Detail 4569 Not Applicable  
    polypeptide ENSMUSP00000042153 Ensembl | MGI Sequence Detail 554 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 213
      cDNA 213

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-33647, MGI:1917554, MGI:2140263, MGI:2140561
    References
    more
    • Summaries
      All 58
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 19
    • Earliest
      J:62630 Chu CC, et al., Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. Mol Immunol. 1998 Jun;35(8):487-502
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory