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Gramd1a Gene Detail
Summary
  • Symbol
    Gramd1a
  • Name
    GRAM domain containing 1A
  • Synonyms
    1300003M23Rik, D7Bwg0611e
  • Feature Type
    protein coding gene
  • IDs
    MGI:105490
    NCBI Gene: 52857
  • Alliance
    genome feature page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30829552-30855321 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 19.30 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    812 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105490
 protein coding gene Chr7:30829552-30855374 (-)
129S1/SvImJ ENSMUSG00200022139
 protein coding gene Chr7:20597629-20623638 (-)
A/J ENSMUSG00195040258
 protein coding gene Chr7:23274831-23299930 (-)
AKR/J ENSMUSG00220042974
 protein coding gene Chr7:21177844-21202931 (+)
BALB/cJ ENSMUSG00180015346
 protein coding gene Chr7:21334317-21359414 (-)
C3H/HeJ ENSMUSG00175033354
 protein coding gene Chr7:22418730-22443752 (-)
C57BL/6NJ ENSMUSG00215011310
 protein coding gene Chr7:20520901-20545923 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029563
 protein coding gene Chr7:30332703-30358563 (-)
CAST/EiJ ENSTCUG00005048141
 protein coding gene Chr7:22306233-22331290 (-)
CBA/J ENSMUSG00210025099
 protein coding gene Chr7:21581336-21606355 (-)
DBA/2J ENSMUSG00185049593
 protein coding gene Chr7:24656071-24681075 (-)
FVB/NJ ENSMUSG00205011349
 protein coding gene Chr7:21330817-21355840 (-)
JF1/MsJ ENSUMUG00000035877
 protein coding gene Chr7:29097487-29122467 (-)
LP/J ENSMUSG00230051959
 protein coding gene Chr7:29832115-29857204 (-)
NOD/ShiLtJ ENSMUSG00190007935
 protein coding gene Chr7:20999117-21024211 (-)
NZO/HlLtJ ENSMUSG00225024357
 protein coding gene Chr7:28662615-28687581 (-)
PWK/PhJ ENSLUMG00010020182
 protein coding gene Chr7:21030389-21055280 (-)
SPRET/EiJ ENSMSPG00010005140
 protein coding gene Chr7:20400603-20422159 (-)
WSB/EiJ ENSIUOG00005050703
 protein coding gene Chr7:15275528-15301629 (-)



Homology
more
  • Human Ortholog
    GRAMD1A, GRAM domain containing 1A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GRAMD1A, GRAM domain containing 1A
  • Synonyms
    KIAA1533, LAMa
  • Links
    NCBI Gene ID: 57655
    UniProt: Q96CP6

  • Chr Location
    19q13.11; chr19:34994727-35026471 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    684
  • Tissues
    7
  • cDNA Data
    112
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001248 Ensembl Gene Model | MGI Sequence Detail 25770 C57BL/6J ±  kb
transcript ENSMUST00000001280 Ensembl | MGI Sequence Detail 2713 Not Applicable  
polypeptide ENSMUSP00000001280 Ensembl | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 114
    cDNA 112
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-33162, MGI:1918998, MGI:2141930, MGI:2142256
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:384229 Liu J, et al., Macrophage MERTK restrains GRAMD1A-driven mitochondrial oxysterol trafficking to limit colitis. Redox Biol. 2026 Apr 20;93:104174
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory