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Tnni1 Gene Detail
Summary
  • Symbol
    Tnni1
  • Name
    troponin I, skeletal, slow 1
  • Synonyms
    2700018B22Rik, ssTnI
  • Feature Type
    protein coding gene
  • IDs
    MGI:105073
    NCBI Gene: 21952
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
  • Regulated by
    Rr512 (1 regulatory region)
Location &
Maps
more
  • Sequence Map
    Chr1:135709252-135738727 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 59.28 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1103 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105073
 protein coding gene Chr1:135707172-135738727 (+)
129S1/SvImJ ENSMUSG00200008057
 protein coding gene Chr1:133323644-133353509 (+)
A/J ENSMUSG00195015174
 protein coding gene Chr1:132397597-132425901 (+)
AKR/J ENSMUSG00220046812
 protein coding gene Chr1:132275793-132305667 (+)
BALB/cJ ENSMUSG00180011020
 protein coding gene Chr1:132937157-132966590 (+)
C3H/HeJ ENSMUSG00175006404
 protein coding gene Chr1:132641696-132669990 (+)
C57BL/6NJ ENSMUSG00215010832
 protein coding gene Chr1:132638996-132668441 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014643
 protein coding gene Chr1:127387387-127419893 (+)
CAST/EiJ ENSTCUG00005035264
 protein coding gene Chr1:131571163-131599353 (+)
CBA/J ENSMUSG00210013862
 protein coding gene Chr1:132572030-132600331 (+)
DBA/2J ENSMUSG00185028150
 protein coding gene Chr1:136946902-136976772 (+)
FVB/NJ ENSMUSG00205002117
 protein coding gene Chr1:131907724-131936016 (+)
JF1/MsJ ENSUMUG00000042623
 protein coding gene Chr1:136070950-136100730 (+)
LP/J ENSMUSG00230038066
 protein coding gene Chr1:136471800-136501235 (+)
NOD/ShiLtJ ENSMUSG00190002626
 protein coding gene Chr1:132586091-132614382 (+)
NZO/HlLtJ ENSMUSG00225017652
 protein coding gene Chr1:140238188-140268069 (+)
PWK/PhJ ENSLUMG00010024123
 protein coding gene Chr1:131695596-131725416 (+)
SPRET/EiJ ENSMSPG00010011544
 protein coding gene Chr1:134500114-134526832 (+)
WSB/EiJ ENSIUOG00005028185
 protein coding gene Chr1:132349032-132377200 (+)



Homology
more
  • Human Ortholog
    TNNI1, troponin I1, slow skeletal type
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TNNI1, troponin I1, slow skeletal type
  • Synonyms
    SSTNI, TNN1
  • Links
    NCBI Gene ID: 7135
    UniProt: P19237

  • Chr Location
    1q32.1; chr1:201403784-201429866 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    863
  • Tissues
    54
  • cDNA Data
    126
  • Literature Summary
    47
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21952 NCBI Gene Model | MGI Sequence Detail 29476 C57BL/6J ±  kb
    transcript NM_021467 RefSeq | MGI Sequence Detail 1086 ZRU/MplStud  
    polypeptide Q9WUZ5 UniProt | EBI | MGI Sequence Detail 187 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 140
      cDNA 128
      Primer pair 11
      Other 1
      Antibodies 4

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-32113, MGI:1917282, MGI:2138320
    References
    more
    • Summaries
      All 92
      Developmental Gene Expression 47
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:347631 Li C, et al., Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes. Adv Sci (Weinh). 2024 Mar;11(11):e2305992
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory