About   Help   FAQ
Sf3a2 Gene Detail
Summary
  • Symbol
    Sf3a2
  • Name
    splicing factor 3a, subunit 2
  • Synonyms
    66kDa, PRP11, Sap62, SFA66
  • Feature Type
    protein coding gene
  • IDs
    MGI:104912
    NCBI Gene: 20222
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80634569-80640756 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    165 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104912
 protein coding gene Chr10:80634032-80640758 (+)
129S1/SvImJ ENSMUSG00200043893
 protein coding gene Chr10:77260320-77267046 (+)
A/J ENSMUSG00195041949
 protein coding gene Chr10:77655889-77662615 (+)
AKR/J ENSMUSG00220047620
 protein coding gene Chr10:77253582-77260308 (+)
BALB/cJ ENSMUSG00180047248
 protein coding gene Chr10:77666363-77673090 (+)
C3H/HeJ ENSMUSG00175046844
 protein coding gene Chr10:77537111-77543837 (+)
C57BL/6NJ ENSMUSG00215052015
 protein coding gene Chr10:77278969-77285695 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015602
 protein coding gene Chr10:74799292-74805577 (+)
CAST/EiJ ENSTCUG00005048050
 protein coding gene Chr10:77164877-77171180 (+)
CBA/J ENSMUSG00210045327
 protein coding gene Chr10:77393148-77399874 (+)
DBA/2J ENSMUSG00185050275
 protein coding gene Chr10:77735577-77742303 (+)
FVB/NJ ENSMUSG00205044733
 protein coding gene Chr10:77448376-77455102 (+)
JF1/MsJ ENSUMUG00000053145
 protein coding gene Chr10:78966882-78973641 (+)
LP/J ENSMUSG00230050056
 protein coding gene Chr10:79505208-79511934 (+)
NOD/ShiLtJ ENSMUSG00190049863
 protein coding gene Chr10:77649298-77656024 (+)
NZO/HlLtJ ENSMUSG00225050960
 protein coding gene Chr10:83791702-83798428 (+)
PWK/PhJ ENSLUMG00010038695
 protein coding gene Chr10:77327240-77334009 (+)
SPRET/EiJ ENSMSPG00010042595
 protein coding gene Chr10:78943395-78950006 (+)
WSB/EiJ ENSIUOG00005044711
 protein coding gene Chr10:77353038-77359763 (+)



Homology
more
  • Human Ortholog
    SF3A2, splicing factor 3a subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SF3A2, splicing factor 3a subunit 2
  • Synonyms
    PRP11, PRPF11, SAP62, SF3a66
  • Links
    NCBI Gene ID: 8175
    UniProt: Q15428

  • Chr Location
    19p13.3; chr19:2236823-2248672 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    648
  • Tissues
    24
  • cDNA Data
    51
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20222 NCBI Gene Model | MGI Sequence Detail 6188 C57BL/6J ±  kb
transcript NM_013651 RefSeq | MGI Sequence Detail 1674 ZRU/MplStud  
polypeptide Q62203 UniProt | EBI | MGI Sequence Detail 475 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    Genomic 2
    cDNA 54
    Primer pair 4

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-29066, MGI:2143796
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory