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Selenbp2 Gene Detail
Summary
  • Symbol
    Selenbp2
  • Name
    selenium binding protein 2
  • Synonyms
    acetaminophen-binding protein, AP56, Lpsb2
  • Feature Type
    protein coding gene
  • IDs
    MGI:104859
    NCBI Gene: 20342
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:94600880-94611713 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.74 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    362 from dbSNP Build 142
  • Strain Annotations
    16
  • PCR
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104859
 protein coding gene Chr3:94600863-94611720 (+)
129S1/SvImJ ENSMUSG00200042682
 protein coding gene Chr3:91257403-91268249 (+)
A/J ENSMUSG00195044937
 protein coding gene Chr3:91584683-91595527 (+)
AKR/J ENSMUSG00220048824
 protein coding gene Chr3:89971785-89982629 (+)
BALB/cJ ENSMUSG00180037403
 protein coding gene Chr3:91566564-91577406 (+)
C3H/HeJ ENSMUSG00175023723
 protein coding gene Chr3:91228385-91239229 (+)
C57BL/6NJ ENSMUSG00215021949
 protein coding gene Chr3:91945238-91956095 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005045423
 protein coding gene Chr3:91776619-91787458 (+)
CBA/J ENSMUSG00210050292
 protein coding gene Chr3:91765877-91776723 (+)
DBA/2J ENSMUSG00185036598
 protein coding gene Chr3:92083249-92094106 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000031467
 protein coding gene Chr3:91087426-91098272 (+)
LP/J ENSMUSG00230039959
 protein coding gene Chr3:94120923-94131767 (+)
NOD/ShiLtJ ENSMUSG00190031556
 protein coding gene Chr3:92247550-92258382 (+)
NZO/HlLtJ ENSMUSG00225010927
 protein coding gene Chr3:96528178-96539019 (+)
PWK/PhJ ENSLUMG00010050113
 protein coding gene Chr3:91061136-91071973 (+)
SPRET/EiJ ENSMSPG00010044145
 protein coding gene Chr3:91374593-91385425 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SELENBP1, selenium binding protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SELENBP1, selenium binding protein 1
  • Synonyms
    EHMTO, HEL-S-134P, hSBP, LPSB, MTO, SBP56, SP56
  • Links
    NCBI Gene ID: 8991
    UniProt: Q13228

  • Chr Location
    1q21.3; chr1:151364302-151372716 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    693
  • Tissues
    8
  • cDNA Data
    41
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20342 NCBI Gene Model | MGI Sequence Detail 10834 C57BL/6J ±  kb
transcript NM_019414 RefSeq | MGI Sequence Detail 1695 ZRU/MplStud  
polypeptide Q63836 UniProt | EBI | MGI Sequence Detail 472 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • EC
    1.8.3.4
  • InterPro Domains
    IPR008826 Selenium-binding protein
  • GlyGen
    Q63836 2 sites, 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 45
    Genomic 1
    cDNA 42
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-28156
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:28549 Lanfear J, et al., Different patterns of regulation of the genes encoding the closely related 56 kDa selenium- and acetaminophen-binding proteins in normal tissues and during carcinogenesis. Carcinogenesis. 1993 Mar;14(3):335-40
  • Latest
    J:391232 Zhao S, et al., Ablation of Mouse Selenium-Binding Protein 1 and 2 Elevates LDL by Disruption of Cholesterol Efflux and Lipid Metabolism. Int J Mol Sci. 2025 Apr 3;26(7)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory