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Spata13 Gene Detail
Summary
  • Symbol
    Spata13
  • Name
    spermatogenesis associated 13
  • Synonyms
    ESTM11, mKIAA1112
  • Feature Type
    protein coding gene
  • IDs
    MGI:104838
    NCBI Gene: 219140
  • Alliance
    genome feature page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:60871450-61002005 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 31.77 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3717 from dbSNP Build 142
  • Strain Annotations
    27
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104838
 protein coding gene Chr14:60722617-61002005 (+)
129S1/SvImJ ENSMUSG00200041005
 protein coding gene Chr14:49533487-49595364 (+)
129S1/SvImJ ENSMUSGG00200054564
 protein coding gene Chr14:49521384-49521938 (+)
A/J ENSMUSG00195029187
 protein coding gene Chr14:49714781-49777507 (+)
A/J ENSMUSGG00195055018
 protein coding gene Chr14:49702723-49703277 (+)
AKR/J ENSMUSGG00220054513
 protein coding gene Chr14:49049919-49050473 (+)
AKR/J ENSMUSG00220027972
 protein coding gene Chr14:49061978-49124709 (+)
BALB/cJ ENSMUSG00180051507
 protein coding gene Chr14:49336659-49399394 (+)
BALB/cJ ENSMUSGG00180055188
 protein coding gene Chr14:49324600-49325154 (+)
C3H/HeJ ENSMUSGG00175055067
 protein coding gene Chr14:51063926-51064480 (+)
C3H/HeJ ENSMUSG00175042789
 protein coding gene Chr14:51076035-51137915 (+)
C57BL/6NJ ENSMUSG00215048585
 protein coding gene Chr14:49266851-49328718 (+)
C57BL/6NJ ENSMUSGG00215055375
 protein coding gene Chr14:49254748-49255302 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019376
 protein coding gene Chr14:51808190-51939489 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210044597
 protein coding gene Chr14:49702892-49765602 (+)
CBA/J ENSMUSGG00210054695
 protein coding gene Chr14:49690835-49691389 (+)
DBA/2J ENSMUSG00185029570
 protein coding gene Chr14:54873745-54935623 (+)
DBA/2J ENSMUSGG00185057666
 protein coding gene Chr14:54861641-54862195 (+)
FVB/NJ ENSMUSG00205018413
 protein coding gene Chr14:49200535-49262411 (+)
FVB/NJ ENSMUSGG00205054207
 protein coding gene Chr14:49188432-49188986 (+)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055400
 protein coding gene Chr14:66884683-66885237 (+)
LP/J ENSMUSG00230035422
 protein coding gene Chr14:66896784-66958653 (+)
NOD/ShiLtJ ENSMUSG00190045973
 protein coding gene Chr14:49499728-49561590 (+)
NOD/ShiLtJ ENSMUSGG00190054640
 protein coding gene Chr14:49487624-49488178 (+)
NZO/HlLtJ ENSMUSGG00225055301
 protein coding gene Chr14:57229197-57229751 (+)
NZO/HlLtJ ENSMUSG00225045680
 protein coding gene Chr14:57241297-57303164 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010030634
 protein coding gene Chr14:52311073-52439848 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SPATA13, spermatogenesis associated 13
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA13, spermatogenesis associated 13
  • Synonyms
    ARHGEF29, ASEF2
  • Links
    NCBI Gene ID: 221178
    UniProt: Q96N96

  • Chr Location
    13q12.12; chr13:23979802-24307074 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotypes from multigenic genotypes
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable, fertile and overtly normal. Behavioral tests indicate that mutant mice exhibit submissive social hierarchy behavior and females exhibit increased voluntary activity in the dark phase of the light-dark cycle.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    701
  • Tissues
    49
  • cDNA Data
    109
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021990 Ensembl Gene Model | MGI Sequence Detail 130556 C57BL/6J ±  kb
transcript ENSMUST00000160973 Ensembl | MGI Sequence Detail 7467 Not Applicable  
polypeptide ENSMUSP00000123928 Ensembl | MGI Sequence Detail 1244 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 109
    cDNA 109

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-28132, MGI:1353612
References
more
  • Summaries
    All 55
    Developmental Gene Expression 9
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:28401 Bettenhausen B, et al., Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos. Genomics. 1995 Aug 10;28(3):436-41
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory