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Cebpd Gene Detail
Summary
  • Symbol
    Cebpd
  • Name
    CCAAT/enhancer binding protein delta
  • Feature Type
    protein coding gene
  • IDs
    MGI:103573
    NCBI Gene: 12609
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:15705150-15707409 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 10.09 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    117 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103573
 protein coding gene Chr16:15705150-15708895 (+)
129S1/SvImJ ENSMUSG00200043147
 protein coding gene Chr16:12701787-12705530 (+)
A/J ENSMUSG00195033601
 protein coding gene Chr16:12258433-12262180 (+)
AKR/J ENSMUSG00220039472
 protein coding gene Chr16:12571020-12574766 (+)
BALB/cJ ENSMUSG00180029213
 protein coding gene Chr16:12500037-12503780 (+)
C3H/HeJ ENSMUSG00175047867
 protein coding gene Chr16:12644797-12648544 (+)
C57BL/6NJ ENSMUSG00215031112
 protein coding gene Chr16:12365889-12369635 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0034007
 pseudogene Chr16:12418216-12419394 (+)
CAST/EiJ ENSTCUG00005039523
 protein coding gene Chr16:12526918-12530661 (+)
CBA/J ENSMUSG00210045087
 protein coding gene Chr16:12661131-12664878 (+)
DBA/2J ENSMUSG00185028410
 protein coding gene Chr16:12607268-12611013 (+)
FVB/NJ ENSMUSG00205044992
 protein coding gene Chr16:12616625-12620370 (+)
JF1/MsJ ENSUMUG00000046598
 protein coding gene Chr16:12671436-12675193 (+)
LP/J ENSMUSG00230039102
 protein coding gene Chr16:15185223-15188968 (+)
NOD/ShiLtJ ENSMUSG00190027865
 protein coding gene Chr16:12747242-12750987 (+)
NZO/HlLtJ ENSMUSG00225030672
 protein coding gene Chr16:18430995-18434740 (+)
PWK/PhJ ENSLUMG00010048096
 protein coding gene Chr16:12559436-12563196 (+)
SPRET/EiJ ENSMSPG00010039211
 protein coding gene Chr16:12565876-12569626 (+)
WSB/EiJ ENSIUOG00005037752
 protein coding gene Chr16:12713014-12716758 (+)



Homology
more
  • Human Ortholog
    CEBPD, CCAAT enhancer binding protein delta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEBPD, CCAAT enhancer binding protein delta
  • Synonyms
    C/EBP-delta, CELF, CRP3, NF-IL6-beta
  • Links
    NCBI Gene ID: 1052
    UniProt: P49716

  • Chr Location
    8q11.21; chr8:47736913-47738164 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 2 alleles in 3 genetic backgrounds
    8 phenotypes from multigenic genotypes
    45 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable and healthy and perform normally on several behavioral tasks, but display enhanced contextual fear conditioning. Mice homozygous for a second knock-out allele exhibit nearly normal or only slightly impaired adipocyte differentiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    16
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    804
  • Tissues
    160
  • cDNA Data
    41
  • Literature Summary
    25
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12609 NCBI Gene Model | MGI Sequence Detail 2260 C57BL/6J ±  kb
    transcript NM_007679 RefSeq | MGI Sequence Detail 2260 ZRU/MplStud  
    polypeptide Q00322 UniProt | EBI | MGI Sequence Detail 268 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 55
      Genomic 5
      cDNA 42
      Primer pair 5
      Other 3
      Antibodies 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-24458
    References
    more
    • Summaries
      All 174
      Developmental Gene Expression 25
      Gene Ontology 16
      Phenotypes 45
    • Earliest
      J:23758 Cao Z, et al., Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 1991 Sep;5(9):1538-52
    • Latest
      J:365250 Hofwimmer K, et al., IL-1beta promotes adipogenesis by directly targeting adipocyte precursors. Nat Commun. 2024 Sep 11;15(1):7957
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory