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Smr2 Gene Detail
Summary
  • Symbol
    Smr2
  • Name
    submaxillary gland androgen regulated protein 2
  • Synonyms
    MSG2
Location &
Maps
more
  • Sequence Map
    Chr5:88234415-88256912 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM, cytoband E2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    639 from dbSNP Build 142
  • Strain Annotations
    28
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102762
 protein coding gene Chr5:88234415-88256912 (+)
129S1/SvImJ ENSMUSGG00200054645
 protein coding gene Chr5:84003470-84007208 (+)
129S1/SvImJ ENSMUSG00200007235
 protein coding gene Chr5:83986336-83996875 (+)
A/J ENSMUSG00195025514
 protein coding gene Chr5:83137669-83148212 (+)
A/J ENSMUSGG00195055336
 protein coding gene Chr5:83154807-83158544 (+)
AKR/J ENSMUSGG00220054855
 protein coding gene Chr5:83294867-83298604 (+)
AKR/J ENSMUSG00220011363
 protein coding gene Chr5:83277729-83288272 (+)
BALB/cJ ENSMUSG00180021473
 protein coding gene Chr5:82989338-82999889 (+)
BALB/cJ ENSMUSGG00180055454
 protein coding gene Chr5:83006485-83010222 (+)
C3H/HeJ ENSMUSGG00175054783
 protein coding gene Chr5:85082105-85085843 (+)
C3H/HeJ ENSMUSG00175037023
 protein coding gene Chr5:85064959-85075510 (+)
C57BL/6NJ ENSMUSGG00215055486
 protein coding gene Chr5:83847865-83851602 (+)
C57BL/6NJ ENSMUSG00215027373
 protein coding gene Chr5:83830727-83841270 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005031963
 protein coding gene Chr5:82693278-82703998 (+)
CBA/J ENSMUSG00210005733
 protein coding gene Chr5:83879775-83890326 (+)
CBA/J ENSMUSGG00210054936
 protein coding gene Chr5:83896921-83900658 (+)
DBA/2J ENSMUSGG00185057855
 protein coding gene Chr5:85816145-85819881 (+)
DBA/2J ENSMUSG00185038870
 protein coding gene Chr5:85798999-85809550 (+)
FVB/NJ ENSMUSGG00205054287
 protein coding gene Chr5:82701375-82705112 (+)
FVB/NJ ENSMUSG00205017886
 protein coding gene Chr5:82684236-82694780 (+)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055856
 protein coding gene Chr5:90533446-90537183 (+)
LP/J ENSMUSG00230001622
 protein coding gene Chr5:90516312-90526851 (+)
NOD/ShiLtJ ENSMUSG00190027122
 protein coding gene Chr5:82746717-82757268 (+)
NOD/ShiLtJ ENSMUSGG00190054997
 protein coding gene Chr5:82763863-82767600 (+)
NZO/HlLtJ ENSMUSGG00225055329
 protein coding gene Chr5:95557469-95561206 (+)
NZO/HlLtJ ENSMUSG00225008117
 protein coding gene Chr5:95526710-95537314 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010028969
 protein coding gene Chr5:85074307-85086449 (+)
WSB/EiJ ENSIUOG00005026558
 protein coding gene Chr5:85697300-85707850 (+)



Homology
more
  • Human Ortholog
    SMR3B, submaxillary gland androgen regulated protein 3B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMR3B, submaxillary gland androgen regulated protein 3B
  • Synonyms
    P-B, PBII, PRL3, PROL3, SMR1B
  • Links
    NCBI Gene ID: 10879
    UniProt: P02814

  • Chr Location
    4q13.3; chr4:70370093-70390244 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20600 NCBI Gene Model | MGI Sequence Detail 22498 C57BL/6J ±  kb
transcript NM_001252679 RefSeq | MGI Sequence Detail 813 C57BL/6  
polypeptide O09133 UniProt | EBI | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR026288 Submaxillary gland androgen-regulated protein like
Molecular
Reagents
less
  • All nucleic 12
    Genomic 3
    cDNA 9

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-19667
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:391206 Peng J, et al., Targeting G(i/o)-coupled GPCRs to inhibit nociceptors: Insights from the serotonin receptor Htr1b and triptans. Cell Rep Med. 2026 Jul 30;:102949
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory