Caution: These are Prototype Reports for Evaluation Purposes Only!

MGD Full QTL Report For J# 30277

Levitt et al. 1995

Phenotype Information for J30277

Phenotype Class: Disease
Phenotype Mode: Induced
- Induced by: IV exposure to atracurium 20 mg/kg
Phenotype Name: Bronchial hyper-responsiveness
- Phenotype Trait 1: bronchial hyperresponsiveness
- Phenotype Assessment: qualitative
Alternative Keywords: BHR, asthma
Strain/Progenitor Information:
- Strain 1:C57BL/6J
- Strain 1 Comment:NULL
- Strain 2:DBA/2J
- Strain 2 Comment:NULL
Phenotype Comments:NULL

Whole Genome Scan? No
Chromosomes Evaluated:11,13,18
Marker Map Methods:
- panel of BXD markers
Number of Markers in Analysis: NULL
Intermarker Distance: NULL
Comments on Marker Map:NULL
QTL Detection Method:LOD
- Other QTL Detection Method: NULL
Significance Threshold for QTL Detection: > 2 LOD
- Significance Threshold Comment:NULL
QTL Estimation Method: interval mapping
- Other QTL Detection Method: NULL
Comments on QTL Estimation Model Used: NULL
QTL Mapping Software
- Map Manager RWE
- MapMaker/QTL
- Other QTL Mapping Software: NULL

QTL Detection Method: LOD
Table of Linked Markers:

QTL Symbol Linked Marker Symbol Association Score P Value Chromosome

Aib Iapls1-13 > 2.0 NULL 13
QTL Estimation: Chromosome 1
- Chromosome: 13
- Location: Peak LOD score of 2.43 4 cM distal to Iapls1-13
- % Phenotypic Variation Accounted For: 43.8%
- Confidence Interval for QTL Estimation: NULL
Comments:NULL

QTL Symbol	Linked Marker Symbol	Association Score	P Value	Chromosome
Aib	Iapls1-13	> 2.0	NULL	13

QTL Symbol(s)	Candidate Gene Symbol	Chromosome	Gene Name
Aibd	Iapls1-13	13	intracisternal A particle, lymphocyte specific 1-13

1) Peak LOD of 2.43 obtained with extreme phenotypes (BXD-2,-6, -18,-32) included; LOD score of 2.85 obtained when all BXD strains included.