Caution: These are Prototype Reports for Evaluation Purposes Only!

MGD QTL Summary Report

J20991

Phenotype Class: Immunologic Disease

Phenotype Name: Susceptibility to Lupus



QTL Symbol Most Tightly Linked Marker Trait Chromosome % Phenotype Variation Accounted for by the QTL Candidate Gene Symbols
Lbw1 tnfa Mortality 17 NULL tnfa
Lbw1 tnfa Antichromatin antibody production 18 NULL tnfa
Lbw1 tnfa Glomerulonephritis (GN) 17 NULL Hsp68
Lbw2 D4Nds2 Mortality 4 NULL NULL
Lbw2 D4Nds2 Glomerulonephritis (GN) 4 NULL Bmfr1
Lbw3 D5Mit101 Mortality 5 NULL NULL
Lbw4 D6Mit25 Mortality 6 NULL Il5r, Tnfr1
Lbw5 Ngfg Mortality 7 NULL NULL
Lbw6 D18Mit8 Mortality 18 NULL NULL
Lbw6 D18Mit8 Glomerulonephritis (GN) 18 NULL NULL
Lbw7 D1Mit36 Antichromatin antibody production 1 NULL Cd28, Ctla4, Bcl2, Il10
Lbw8 Il4 Antichromatin antibody production 11 NULL Il4, Il5, Irf1, Trp53
Sbw1 D1Nds1 Splenomegaly 1 NULL Cd28, Ctla4, Bcl2, Il10
Sbw2 D4Mit9 Splenomegaly 4 NULL Bmfr1

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