NOD.Cg-H2-K1<d-em1Dvs> H2-Ab1<g7-em1Dvs> H2-D1<b-em5Dvs> Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(CD2-Tcra6H9,Cd4-Tcrb6H9)2Dvs/DvsJ Strain Detail MGI Mouse MGI:7614247

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NOD.Cg-H2-K1^d-em1Dvs H2-Ab1^g7-em1Dvs H2-D1^b-em5Dvs Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(CD2-Tcra6H9,Cd4-Tcrb6H9)2Dvs/DvsJ Strain Detail

Summary

Strain Name

NOD.Cg-H2-K1^d-em1Dvs H2-Ab1^g7-em1Dvs H2-D1^b-em5Dvs Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(CD2-Tcra6H9,Cd4-Tcrb6H9)2Dvs/DvsJ
Attributes

congenic, endonuclease-mediated mutation, mutant strain, transgenic
MGI ID

MGI:7614247

Other IDs

JAX:035479

5 associated mutations

Mutation Carried	Marker
H2-Ab1^g7-em1Dvs	H2-Ab1
H2-D1^b-em5Dvs	H2-D1
H2-K1^d-em1Dvs	H2-K1
Tg(CD2-Tcra6H9,Cd4-Tcrb6H9)2Dvs	Tg(CD2-Tcra6H9,Cd4-Tcrb6H9)2Dvs
Tg(HLA-DQA1,HLA-DQB1)1Dv	Tg(HLA-DQA1,HLA-DQB1)1Dv

Earliest

J:346039 Racine JJ, et al., HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice. J Immunol. 2023 Dec 15;211(12):1792-1805
All

1

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