Sequence Detail

ID/Version

Q2KHI9 Q3V370 Q6P6J6 Q9D344 (UniProt | EBI)

Last sequence update: 2007-09-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DNA helicase MCM9; EC=3.6.4.12 {ECO:0000250|UniProtKB:Q9NXL9};AltName: Full=Mini-chromosome maintenance deficient domain-containing protein 1;AltName: Full=Minichromosome maintenance 9;

Provider

SWISS-PROT

Sequence

Polypeptide 1134 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mcm9	minichromosome maintenance 9 homologous recombination repair factor	57	103	3	32

Sequence references in MGI

J:97949 Yoshida K, Identification of a novel cell-cycle-induced MCM family protein MCM9. Biochem Biophys Res Commun. 2005 Jun 3;331(2):669-74
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:177420 Hartford SA, et al., Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17702-7
J:187623 Lutzmann M, et al., MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination. Mol Cell. 2012 Aug 24;47(4):523-34
J:203320 Park J, et al., The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination. Mol Cell Biol. 2013 Apr;33(8):1632-44
J:228092 Traver S, et al., MCM9 Is Required for Mammalian DNA Mismatch Repair. Mol Cell. 2015 Sep 3;59(5):831-9