Symbol Name ID

Nlrp3 NLR family, pyrin domain containing 3 MGI:2653833

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10 matching Alleles (1 Gene/Marker represented)

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                                                Allele Symbol
Name                                                   Chr               Synonyms                          Category                                                             Phenotypic Classes                                                                      Human Diseases                    

Nlrp3tm1Bhk
NLR family, pyrin domain containing 3; targeted mutation 1, Beverly H Koller                             11                                      Targeted (knock-out)             homeostasis, immune                                                                                                                                                       

Nlrp3tm1Flv
NLR family, pyrin domain containing 3; targeted mutation 1, Richard A Flavell                            11   Cias1-, cryopyrin, Nalp3-, Nlrp3-  Targeted (knock-out)             digestive/alimentary, homeostasis, immune, mortality/aging                                                         Muckle-Wells Syndrome; MWS 191900                      

Nlrp3tm1Hhf
NLR family, pyrin domain containing 3; targeted mutation 1, Hal M Hoffman                                11   Nlrp3A350VneoR                     Targeted (knock-in)              digestive/alimentary, growth/size, hematopoietic, homeostasis, immune, integument, mortality/aging, renal/urinary  Muckle-Wells Syndrome; MWS 191900                      

Nlrp3tm1Tsc
NLR family, pyrin domain containing 3; targeted mutation 1, Jurg Tschopp                                 11   NALP3-                             Targeted (Reporter)              immune                                                                                                                                                                    

Nlrp3tm1Vmd
NLR family, pyrin domain containing 3; targeted mutation 1, Vishva M Dixit                               11   Cias1-, Nalp3-                     Targeted (knock-out)             homeostasis, immune                                                                                                                                                       

Nlrp3tm1Wstr
NLR family, pyrin domain containing 3; targeted mutation 1, Warren Strober                              11   Nlrp3R258W                         Targeted (Floxed/Frt)            growth/size, hematopoietic, immune, integument, liver/biliary, mortality/aging, reproductive                       Muckle-Wells Syndrome; MWS 191900                      

Nlrp3tm2Hhf
NLR family, pyrin domain containing 3; targeted mutation 2, Hal M Hoffman                                11   Nlrp3L351PneoR                     Targeted (knock-in)              immune, mortality/aging                                                                                            Familial Cold Autoinflammatory Syndrome 1; FCAS1 120100

Nlrp3tm3Hhf
NLR family, pyrin domain containing 3; targted mutation 3, Hal M Hoffman                                 11   Nlrp3D301NneoR                     Targeted (knock-in)              no abnormal phenotype observed                                                                                                                                            

Nlrp3tm1(KOMP)Vlcg
NLR family, pyrin domain containing 3; targeted mutation 1, Velocigene                            11                                      Targeted (knock-out)
(Cell Line)                                                                                                                                                                            

Nlrp3tm1(NCOM)Mfgc
NLR family, pyrin domain containing 3; targeted mutation 1, Mammalian Functional Genomics Centre  11                                      Targeted (knock-out)
(Cell Line)