Symbol Name ID

Lrrk2 leucine-rich repeat kinase 2 MGI:1913975

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14 matching Alleles (1 Gene/Marker represented)

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                                         Allele Symbol
Name                                            Chr     Synonyms                 Category                                       Phenotypic Classes                           Human Diseases

Lrrk2tm1.1Cai
leucine-rich repeat kinase 2; targeted mutation 1.1, Huaibin Cai                         15                   Targeted (knock-out)             hematopoietic, immune, nervous system                                                

Lrrk2tm1.1Mjff
leucine-rich repeat kinase 2; targeted mutation 1.1, The Michael J Fox Foundation       15   Lrrk2tm1.1Youy  Targeted (knock-out)                                                                                                  

Lrrk2tm1.1Npa
leucine-rich repeat kinase 2; targeted mutation 1.1, Novartis Pharma AG                  15   LRRK2-G2019S    Targeted (knock-out)             cardiovascular                                                                       

Lrrk2tm1.1Shn
leucine-rich repeat kinase 2; targeted mutation 1.1, Jie Shen                            15   Lrrk2R1441C     Targeted (knock-in)              behavior, endocrine/exocrine, homeostasis, nervous system                            

Lrrk2tm1.2Npa
leucine-rich repeat kinase 2; targeted mutation 1.2, Novartis Pharma AG                  15                   Targeted (other)                 cardiovascular, homeostasis, pigmentation, renal/urinary, respiratory                

Lrrk2tm1Arte
leucine-rich repeat kinase 2; targeted mutation 1, TaconicArtemis                         15                   Targeted (knock-out)                                                                                                  

Lrrk2tm1Mjfa
leucine-rich repeat kinase 2; targeted mutation 1, Matthew Farrer                         15                   Targeted (knock-out)             cellular, nervous system                                                             

Lrrk2tm1Tmd
leucine-rich repeat kinase 2; targeted mutation 1, Ted Dawson                              15                   Targeted (knock-out)             behavior, integument, mortality/aging                                                

Lrrk2tm2.1Npa
leucine-rich repeat kinase 2; targeted mutation 2.1, Novartis Pharma AG                  15   LRRK2-D1994S    Targeted (knock-in)              pigmentation, renal/urinary                                                          

Lrrk2tm2.1Shn
leucine-rich repeat kinase 2; targeted mutation 2.1, Jie Shen                            15   Lrrk2KO1        Targeted (knock-out)             cellular, immune, pigmentation, renal/urinary                                        

Lrrk2tm2Mjfa
leucine-rich repeat kinase 2; targeted mutation 2, Matthew Farrer                         15                   Targeted (knock-in)              no abnormal phenotype observed                                                       

Lrrk2tm3.1Shn
leucine-rich repeat kinase 2; targeted mutation 3.1, Jie Shen                            15   Lrrk2KO2        Targeted (knock-out)             renal/urinary                                                                        

Lrrk2tm1(KOMP)Mbp
leucine-rich repeat kinase 2; targeted mutation 1, Mouse Biology Program, UCDavis    15                   Targeted (knock-out)
(Cell Line)                                                                                       

Lrrk2tm1(KOMP)Wtsi
leucine-rich repeat kinase 2; targeted mutation 1, Wellcome Trust Sanger Institute  15                   Targeted (knock-out)
(Cell Line)